New knife may ease pain after throat surgery for swallowing problems

NCT ID NCT05272046

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compared two different surgical knives used during a procedure called POEM, which treats swallowing disorders by cutting throat muscles. 104 adults were randomly assigned to receive either a standard monopolar knife or a newer bipolar knife (Speedboat-RS2). The goal was to see if the bipolar knife caused less pain after the procedure and made the surgery faster and easier.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

monopolar current cutting knife and bipolar RFA knife (Speedboat-RS2)

What this could lead to

If the bipolar knife works better, it could mean less pain after POEM and a smoother procedure for patients with swallowing disorders.

What could go wrong

This is a small, completed study comparing two tools already in use, so the results may not apply to all patients or settings. The main risk is that the bipolar knife may not reduce pain as hoped.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Deglutition Disorders dyskinesia of esophagus Esophageal Achalasia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Asian Institute of Gastroenterology (AIG) Hospitals

    Hyderabad, 500082, India

  • Baylor College of Medicine

    Houston, Texas, 77030, United States

  • Navarra Hospital Complex - Navarra Hospital

    Pamplona, 31008, Spain