New study aims to ease breathing and swallowing problems in kids with brain conditions

NCT ID NCT05455359

First seen Jan 11, 2026 · Last updated May 23, 2026 · Updated 19 times

Summary

This study looks at whether stomach and esophagus movement problems increase the risk of aspiration (food or liquid going into the lungs) in children with neurologic impairment. About 120 children aged 5-21 who rely on feeding tubes and are at high risk for aspiration pneumonia will take two different drugs—prucalopride and famotidine—over 10 weeks to compare their effects on symptoms. The goal is to find a better way to manage these symptoms and improve quality of life.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Boston Children's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.