Trained donor cells take aim at Hard-to-Treat blood cancers

NCT ID NCT02494167

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 29 times

Summary

This early-phase study tests a new therapy using specially trained immune cells from a donor to target and kill cancer cells in people with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) whose disease has returned or not gone away after a stem cell transplant. The cells are grown in a lab to recognize four proteins common on these cancer cells. The main goal is to find the safest dose and see if the cells can shrink or control the cancer.

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Contacts and locations

Locations

  • Houston Methodist Hospital

    Houston, Texas, 77030, United States

  • Texas Children's Hospital

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.