Engineered immune cells plus chickenpox vaccine take on childhood cancers

NCT ID NCT01953900

First seen Jan 30, 2026 · Last updated May 03, 2026 · Updated 18 times

Summary

This early-stage study tests a new treatment for advanced osteosarcoma and neuroblastoma that has not responded to standard therapies. Researchers take a patient's own immune cells, add a special receptor to help them recognize and attack cancer cells, and combine them with a chickenpox vaccine to help the cells last longer in the body. The main goals are to find a safe dose and understand side effects in about 26 participants.

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Contacts and locations

Locations

  • Houston Methodist Hospital

    Houston, Texas, 77030, United States

  • Texas Children's Hospital

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.