Pee power: urine test may replace needles for brittle bone diagnosis

NCT ID NCT02531087

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study is testing whether a urine test can help identify different genetic types of osteogenesis imperfecta (OI), a rare condition that causes bones to break easily. Researchers will measure certain collagen peptides in the urine of 25 people with OI. If successful, this could replace the need for blood or skin biopsies to determine the OI subtype.

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Conditions

The condition(s) this trial relates to.

osteogenesis imperfecta

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Baylor College of Medicine

    Houston, Texas, 77030, United States

  • Hospital for Special Surgery

    New York, New York, 10021, United States

  • Oregon Health Science University

    Portland, Oregon, 97239, United States

  • Shriners Hospital for Children

    Milwauke, Wisconsin, 53201, United States

  • Shriners Hospital for Children

    Montreal, Quebec, H3G 1A6, Canada

  • University of California Los Angeles

    Los Angeles, California, 90095, United States

  • University of Nebraska Medical Center

    Omaha, Nebraska, 68198, United States