Engineered immune cells take on childhood cancers in early trial

NCT ID NCT04377932

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 23 times

Summary

This study tests a new treatment called AGAR T cells for children whose solid tumors (like liver cancer or Wilms tumor) have returned or not responded to standard care. The treatment involves taking a patient's own immune cells, adding genes to help them recognize and attack tumor cells, and giving them back. The main goal is to find a safe dose and understand side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Texas Children's Hospital

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.