Engineered immune cells take aim at Hard-to-Treat blood cancer

NCT ID NCT04219163

First seen Oct 31, 2025 · Last updated May 16, 2026 · Updated 25 times

Summary

This early-stage study tests a new treatment for adults with acute myeloid leukemia (AML) that has returned or not responded to standard therapy. The treatment uses the patient's own immune cells, called T cells, which are modified in a lab to recognize and attack AML cells carrying a protein called CLL-1. The goal is to see if this CAR-T cell therapy is safe and can shrink tumors, with 18 participants enrolled.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Texas Children's Hospital

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.