Invisalign offers hope for safer smiles in osteogenesis imperfecta

NCT ID NCT04815564

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether Invisalign clear aligners can safely straighten teeth in people with Osteogenesis Imperfecta (OI), a condition that makes bones brittle and dental work risky. About 57 participants aged 12 to 40 with mild to moderate teeth misalignment will receive treatment at three centers. The goal is to see if clear aligners are effective and less invasive than traditional braces, potentially creating new guidelines for orthodontic care in OI.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • McGill University

    Montreal, Quebec, H3A 1G1, Canada

  • Nidcr/Nih

    Bethesda, Maryland, 20892-1470, United States

  • University of California Los Angeles

    Los Angeles, California, 90095, United States

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