Invisalign offers hope for safer smiles in brittle bone disease
NCT ID NCT04815564
First seen Jan 05, 2026 · Last updated May 14, 2026 · Updated 18 times
Summary
This study tests whether Invisalign clear aligners can safely straighten teeth in people with Osteogenesis Imperfecta (OI), a condition that makes bones brittle and dental work risky. About 57 participants aged 12 to 40 with mild to moderate dental misalignment will receive treatment at three centers. The goal is to see if clear aligners are effective and safer than traditional braces for this group.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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McGill University
Montreal, Quebec, H3A 1G1, Canada
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Nidcr/Nih
Bethesda, Maryland, 20892-1470, United States
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University of California Los Angeles
Los Angeles, California, 90095, United States
Conditions
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