Invisalign offers hope for safer smiles in osteogenesis imperfecta
NCT ID NCT04815564
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether Invisalign clear aligners can safely straighten teeth in people with Osteogenesis Imperfecta (OI), a condition that makes bones brittle and dental work risky. About 57 participants aged 12 to 40 with mild to moderate teeth misalignment will receive treatment at three centers. The goal is to see if clear aligners are effective and less invasive than traditional braces, potentially creating new guidelines for orthodontic care in OI.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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McGill University
Montreal, Quebec, H3A 1G1, Canada
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Nidcr/Nih
Bethesda, Maryland, 20892-1470, United States
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University of California Los Angeles
Los Angeles, California, 90095, United States