Brittle bone disease linked to severe teeth misalignment – new study investigates
NCT ID NCT02934451
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at teeth misalignment and neck defects in people with moderate to severe osteogenesis imperfecta (OI), a rare condition that causes bones to break easily. Researchers will use scans of the teeth, jaw, and neck to measure these problems in 75 participants aged 10 and older. The goal is to better understand dental issues in OI to improve quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could point toward better dental treatments for people with OI, improving chewing and quality of life.
What could go wrong
This is an observational study, not a treatment trial. It only measures problems, so it won't directly provide a new therapy. Results may not apply to all OI types.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Baylor College of Medicine
Houston, Texas, 77030, United States
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Shriners Hospital for Children
Montreal, Quebec, H3G 1A6, Canada
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University of California Los Angeles
Los Angeles, California, 90095, United States