PREGNANCY

This study is testing if it's safe and practical for pregnant people with type 1 or type 2 diabetes to continue using their personal insulin pump during labor. Currently, they are often asked to switch to insulin given through an IV, which can be stressful and may disrupt blood s…

This study is testing whether a nutritional supplement called MitoQ can help women with preeclampsia, a serious pregnancy complication. Researchers will enroll 80 pregnant patients to see if MitoQ improves blood vessel function in the mother and placenta, which could help prolong…

This study aims to see if portable ultrasound devices, guided by artificial intelligence (AI), can help frontline health workers in rural Ethiopia provide better pregnancy care. It will compare two different AI-ultrasound tools against standard care without ultrasound. The goal i…

This study is testing if a daily probiotic supplement can help pregnant women at risk for low iron absorb iron better from their diet and improve their blood health. Researchers want to see if this approach is more comfortable and effective than standard iron pills, which can cau…

This study is testing whether a computer program (AI dashboard) can help doctors and nurses during labor. It aims to see if using the AI tool is as good as standard care at avoiding unplanned C-sections for first-time mothers. The tool provides continuous risk estimates, and rese…

This study is testing whether adding personalized lifestyle coaching from a community health worker to standard remote blood pressure monitoring helps women better manage their heart health after having high blood pressure during pregnancy. It will involve 240 women who had hyper…

This study is testing if a small, temporary port placed on the skin makes insulin therapy easier for pregnant women with diabetes. Instead of multiple daily needle pokes, insulin is injected through the same port for up to three days. Researchers want to see if this method helps …

This study aims to find out if taking a long-acting insulin twice a day instead of once a day helps pregnant women with pre-existing diabetes better control their blood sugar. Researchers will randomly assign 200 participants to either the once-daily or twice-daily insulin group …

This study aims to find better ways to screen pregnant and new mothers for tuberculosis (TB) in Guinea-Bissau, where the disease is common. Researchers will test new screening tools, including a stool test and a computer program to read chest X-rays, during routine prenatal check…

This study aims to see if a new home pregnancy test (called Clara™) is as accurate as existing tests and easy for people to use correctly at home. About 180 volunteers will take the test at a clinic and answer questions about the instructions. Researchers will compare the volunte…

This study is testing if a simple, non-invasive finger monitor can help doctors decide which pregnant women need extra fluids. It will compare the finger device's readings to a standard heart ultrasound in 88 women, including those with a serious condition called preeclampsia. Th…

This study offers free dental check-ups, cleanings, and supplies to pregnant women to help them take better care of their teeth and gums. Researchers want to see if this support improves oral health during pregnancy and leads to better birth outcomes. The study will compare two d…

This study aims to find the best length of time to give blood-thinning medication to new mothers who have a specific genetic trait that increases their risk of developing dangerous blood clots after giving birth. Researchers will look back at the medical records of 100 women with…

This study is testing whether a simple, traditional daily meal made from local foods can help pregnant women in rural Pakistan stay healthier in hot weather and give birth to healthier babies. Researchers will compare about 300 women who eat the special balanced meal with women w…

This study aims to see if providing healthy lifestyle education about diet, exercise, and nutrition to women before they get pregnant or in early pregnancy can improve their heart health and lower the risk of pregnancy complications like gestational diabetes and preeclampsia. Res…

This study tests a counseling program called Healthy Families-PrEP that helps women in rural Uganda use HIV prevention medication (PrEP) when they are trying to get pregnant, during pregnancy, and after giving birth. The goal is to reduce HIV infections in women and prevent passi…

This small pilot study is testing whether eating one pound of fermented poi (a traditional Hawaiian food) daily for four weeks during pregnancy can improve a mother's gut bacteria and lower the risk of developing gestational diabetes. Fifty pregnant women on O'ahu will receive th…

This study aims to see if women are better at taking their daily medication when it comes in one combined pill versus two separate pills. The one pill would provide both HIV prevention and birth control. Researchers will measure how consistently 300 women take each option and ask…

This study is testing a personalized prenatal support program called PTBCARE+ to see if it can lower stress and reduce the risk of early delivery in pregnant people who are at high risk for having a preterm baby. Researchers will compare about 1,200 participants who receive the e…

This study is testing whether a free smartphone app called MI MOM can help prevent health problems during and after pregnancy. It will enroll 500 pregnant adults on Medicaid and compare those using the app—which provides health information, videos, and connections to support—to t…

This study is testing a nutrition education program designed with local communities in northern Ghana. It aims to help first-time pregnant women eat a more varied and nutritious diet to support healthy weight gain. Researchers want to see if this improves the mothers' health know…

This study will test whether virtual doula support improves birth experiences and outcomes for first-time mothers in rural U.S. communities. Researchers will randomly assign 614 pregnant women to receive either virtual doula visits throughout pregnancy and after birth, or usual c…

This study is testing whether a therapy called prolonged exposure, combined with small financial rewards for attending sessions, helps reduce PTSD symptoms in pregnant women. All 30 participants will receive 12 weeks of weekly therapy and be assessed regularly. Researchers will a…

This study aims to see if a moderate exercise program is practical and acceptable for pregnant women who are at increased social risk. It will involve 60 women, with about half participating in a hybrid (in-person and online) exercise program three times a week. The main goal is …

This study is developing and testing a virtual reality (VR) program designed to help first-time mothers prepare for childbirth and support their mental wellbeing. The VR experience uses a labyrinth as a metaphor for the emotional journey of pregnancy and labor. Researchers will e…

This study is testing whether a weekly exercise program, with optional pelvic floor therapy, can help reduce pain and improve movement for pregnant women experiencing pelvic girdle pain. Forty participants will be randomly assigned to either receive the guided sessions or standar…

This study is testing whether using a weighted blanket can help pregnant women who experience leg cramps, poor sleep, anxiety, and stress. Fifty women in their third trimester will try using an 8kg weighted blanket for two weeks, after first going two weeks without it. Researcher…

This study compares two methods for managing pain after a planned C-section. It will test whether adding a small dose of morphine to the spinal anesthesia works better than a numbing injection in the abdominal wall. Researchers will enroll 100 women having planned C-sections to s…

This study is testing an online program called STORK that aims to help first-time expectant couples navigate common sexual changes during pregnancy and after having a baby. The program provides education and skills to help couples maintain their connection and improve sexual sati…

This study is testing if eating milk chocolate during active labor can shorten the pushing stage of childbirth. Researchers will compare 180 healthy pregnant women who eat chocolate to those who do not. The goal is to see if this simple, tasty energy source can make labor easier …

This study is testing if a numbing spray can reduce the pain of getting an IV needle placed before a scheduled C-section. Researchers will compare a 10% lidocaine spray to a placebo spray in 150 women. The goal is to see if the spray makes the common but painful IV insertion proc…

This study will compare two methods for closing the skin after a cesarean delivery: traditional absorbable stitches versus a newer type of absorbable staple placed under the skin. Researchers want to see if the staples lead to shorter surgery times and better-looking scars with l…

This study aims to understand how a mother's environment, lifestyle, and diet during pregnancy affect the health of her twin babies. Researchers will follow 120 women with twin pregnancies and their 240 children for one year, collecting information on air pollution, diet, and oth…

This study aims to understand how different arm positions affect blood pressure readings in pregnant women. Researchers will measure blood pressure in 300 pregnant women with their arms in various common positions during a single clinic visit. The goal is to determine the most ac…

This small pilot study aims to see if a short educational class can help pregnant women feel more confident and knowledgeable about safe exercise. About 30-40 pregnant women will be randomly assigned to either receive standard prenatal information or the standard information plus…

This study aims to understand if certain MS medications taken by mothers before or during pregnancy affect their babies' immune systems. Researchers will follow 111 mother-child pairs to check the babies' blood for immune cell levels, infection rates, and vaccine responses. The g…

This study aims to understand how a natural substance called kynurenine changes during pregnancy in women with chronic kidney disease. Researchers will measure kynurenine levels in 204 pregnant women, with and without kidney disease, to see if lower levels are linked to serious c…

This study aims to understand if a pregnant person's muscle strength and flexibility in their hips, core, and pelvic floor are linked to how they give birth and their recovery. Researchers will follow 376 pregnant people from late pregnancy until 12 weeks after delivery, measurin…

This study aims to understand how the bacteria in a pregnant woman's gut and her diet might influence inflammation in her baby's gut after birth. Researchers will follow 80 pregnant women, some with and some without Inflammatory Bowel Disease (IBD), and their babies for a year. T…

This study aims to understand how sleep affects heart health in pregnant women with low incomes. Researchers will measure sleep patterns at home using wrist monitors and breathing tests in 50 participants. The goal is to gather information to create better sleep screening and sup…

This study aims to measure how pregnancy and breastfeeding affect the levels of CFTR modulator drugs in the body. It will enroll 30 pregnant women with cystic fibrosis who are taking these medications. The goal is to gather safety information to help doctors better counsel women …

This study aims to understand if and how doctors trust artificial intelligence (AI) when it estimates a baby's size from pregnancy ultrasound scans. Over 300 obstetric clinicians will review sample scan cases, comparing AI estimates to traditional methods. Researchers will see if…

This study aims to understand how much leucine, an essential protein building block, healthy pregnant women need during early and late pregnancy. Researchers will measure how the body uses leucine by having 40 participants eat carefully prepared meals and provide breath, urine, a…

This study tests a training program for pregnancy doctors and nurses to help them better counsel patients about workplace rights and accommodations. It will see if this training leads to more documented counseling, fewer job-related problems like wage loss, and better health outc…

This study aims to find out how common certain antibiotic-resistant bacteria are in pregnant women whose water breaks too early. Researchers will follow 250 women from the time their water breaks until they give birth, taking regular swabs to check for these bacteria. The goal is…

This study aims to understand how searching for health information online affects anxiety levels and personal health views in pregnant women. Researchers will survey 80 pregnant women about their internet use, anxiety, and health perceptions. The goal is to gather knowledge, not …