PREGNANCY

This study looks at whether taking insulin glargine twice a day instead of once a day helps pregnant women with type 2 diabetes keep their blood sugar in a healthier range. About 200 pregnant women between 24 and 28 weeks will be randomly assigned to one of two groups. Their bloo…

This study tests whether eating a traditional, balanced meal made from local foods once a day during pregnancy can help women in rural Pakistan handle heat stress better and have healthier babies. Researchers will compare 292 women who eat the meal with those who eat as usual, ch…

This study offers free dental check-ups, cleanings, and supplies to pregnant people with gum disease. It compares two noninvasive oral health methods to see which better reduces gum inflammation and improves pregnancy outcomes. About 160 participants under 20 weeks pregnant with …

This study will check if a simple finger stick blood test gives the same pregnancy hormone (beta-hCG) results as a standard blood draw from the arm. About 40 pregnant women will provide both types of blood samples so researchers can compare the numbers. If finger stick blood work…

This study checks how well a new home pregnancy test works. About 180 women will take the test at a study center and answer questions. Their results will be compared to lab tests to see if the test is easy to use and accurate.

This study will test different combinations of an online program called CARRII to find the best way to help Native women reduce their risk of an alcohol-exposed pregnancy. About 512 women who are at risk will participate for 3 months. The goal is to make the program effective and…

This study tests a personalized support program (PTBCARE+) for pregnant individuals at high risk of delivering early. About 1,228 participants will either receive the program—which includes stress reduction tools, a website/app, and massage—or standard prenatal care. The goal is …

This study tests a new program that teaches pregnant women in Bangladesh how to care for their teeth and gums during their regular prenatal visits. Over 95% of pregnant women in Bangladesh have gum disease, but oral health is not usually part of pregnancy care. The study will com…

This study tests whether teaching women about healthy eating, activity, and other lifestyle habits before or during early pregnancy can improve their heart health and lower the risk of problems like gestational diabetes and preeclampsia. About 200 women at risk for these complica…

This study compares how well women stick to a single daily pill that prevents both HIV and pregnancy versus taking two separate pills. About 300 women without HIV, aged 16-39, will try both methods in a crossover design. The goal is to see if a combined pill makes it easier to st…

This study tests a counseling program called Healthy Families-PrEP that helps women in rural Uganda use HIV prevention pills (PrEP) while trying to get pregnant, during pregnancy, and after giving birth. The goal is to reduce HIV infections in both women and their children. About…

This study compares two ways to manage pain after a planned C-section: a small dose of morphine given with the spinal anesthesia, or a nerve block (TAP block) using numbing medicine. About 100 women will take part, and researchers will measure pain levels, side effects, and recov…

This study tests whether short weekly exercises delivered through a mobile app can help first-time parents manage their emotions and stress during pregnancy. Expecting mothers and fathers in Singapore will use the app, wear a Fitbit, and complete surveys about their well-being an…

This study will test whether using a weighted blanket can reduce nighttime leg cramps, improve sleep quality, and lower anxiety and stress in pregnant women. Fifty women in their third trimester will first go two weeks without the blanket, then two weeks using it. The goal is to …

This study will test whether virtual doula services can improve birth outcomes and satisfaction for first-time mothers living in rural areas. Researchers will recruit 614 pregnant women across the U.S. to compare those who receive virtual doula support with those who do not. The …

This study looks at whether eating milk chocolate during labor can shorten the second stage (the pushing phase). Researchers will compare 180 healthy pregnant women who eat chocolate to those who don't. The goal is to see if a quick energy boost helps labor progress faster.

This study looks at whether a mindfulness-based stress reduction program can help first-time pregnant women feel less anxious, worry less about their baby's health, and improve their overall mental well-being. About 100 women between 12 and 28 weeks of pregnancy will take part. T…

This study looks at whether it is safe and practical for pregnant people with type 1 or type 2 diabetes to keep using their insulin pump during labor, instead of switching to IV insulin. About 30 participants who already use an insulin pump will be allowed to continue using it wh…

This study tests an online program called STORK that helps couples navigate sexual changes during pregnancy and the first year after birth. About 268 couples will be randomly assigned to the program or a waitlist. The goal is to improve sexual satisfaction, reduce distress, and s…

This study compares using an injection port versus single-use needles for giving insulin to pregnant women with diabetes. The goal is to see if the port helps women stick to their insulin schedule and feel more satisfied with their care. About 44 participants will try both method…

This study tests whether a 10% lidocaine spray can reduce the pain of inserting an IV in women scheduled for a C-section. About 150 participants will receive either the spray or a placebo before the IV is placed, and they will rate their pain on a scale from 0 to 10. The goal is …

This study tests whether a weekly exercise program, plus extra pelvic floor therapy if needed, can reduce pelvic girdle pain in pregnant women. About 40 women with pelvic pain will either join the exercise group or receive standard care. The goal is to see if this approach lowers…

This study tests if a new type of absorbable staple can close the skin faster and leave a better-looking scar than the usual method after a C-section. About 237 women having a C-section will be randomly assigned to one of the two closure methods. The main goal is to see if the st…

This study tests a structured education program for first-time pregnant women to reduce fear of childbirth and stress, and increase belief in normal birth. About 72 women will either take the program or get standard care. The goal is to help moms feel more prepared and have a pos…

This study tests whether a type of talk therapy called prolonged exposure plus incentives (PE+) can reduce PTSD symptoms in pregnant patients. Thirty pregnant adults with PTSD will receive weekly therapy sessions for 12 weeks. Researchers will measure changes in PTSD severity and…

This study tests a 4-week virtual reality program designed to help first-time pregnant women feel more confident and less anxious about childbirth. Sixty-eight women will be randomly assigned to use the VR tool or receive standard care. The goal is to see if VR can improve birth …

This observational study follows 111 children born to women with multiple sclerosis who received rituximab or similar drugs before or during pregnancy. Researchers want to see if the drug affects the baby's immune cells, increases infections, or weakens vaccine responses in the f…

This study looks at how pregnant women's online health searches (cyberchondria) relate to their anxiety levels and how they see their own health. About 80 pregnant women will fill out questionnaires. The goal is to understand these connections better, not to test a treatment.

This study works with people who have Primary Ciliary Dyskinesia (PCD) and their doctors to create easy-to-understand resources about fertility and pregnancy safety. About 30 participants will help design and test these materials. The goal is to improve knowledge and care for peo…

This study explores whether a moderate physical activity program (3 times a week, 60-minute sessions, both in-person and online) is practical for pregnant women who face social and economic challenges. Researchers will recruit 60 women, with 30 joining the exercise program and th…

This observational study at Stanford will test if a noninvasive finger monitor can predict how pregnant women, including those with severe preeclampsia, respond to fluids. Researchers will compare the finger device's accuracy to standard heart ultrasound. The goal is to find a si…

This study looks at 376 pregnant women to see if the strength and flexibility of their hips, pelvis, and belly muscles affect how they give birth and whether they have pelvic floor problems after delivery. Researchers will measure these muscles at 36 weeks of pregnancy and follow…

This study looks at how often pregnant women who experience early water breaking carry antibiotic-resistant bacteria. Researchers will follow 250 women in French hospitals, taking samples to track these bacteria over time. The goal is to help doctors choose the right antibiotics …

This study looks at whether training obstetric providers to counsel patients about workplace accommodations helps pregnant women keep their wages, get needed changes at work, and improve health for themselves and their babies. About 400 pregnant patients and their healthcare prov…

This study looks at how cystic fibrosis medications (CFTR modulators) change in the body during pregnancy and after childbirth. Researchers will measure drug levels in the blood, breast milk, and umbilical cord blood of 30 women. The goal is to understand how these drugs behave i…

This study looks at a natural chemical called kynurenine in pregnant women with and without chronic kidney disease. Researchers want to see if lower levels of this chemical are linked to preeclampsia, a serious condition that can harm mothers and babies. About 204 women will give…

This study follows 120 women with twin pregnancies and their 240 babies to understand how things like air pollution, diet, and lifestyle during pregnancy and the first year of life affect growth and health. Researchers will measure pollutants and collect samples to find links bet…

This study tests whether AI-assisted ultrasound devices can help frontline health workers in rural Ethiopia detect pregnancy complications early, potentially reducing deaths of mothers and newborns. About 1,059 pregnant women will be split into three groups: two using different A…

This pilot study will test whether a short educational session about safe exercise during pregnancy can improve women's knowledge, confidence, and physical activity levels. About 30 pregnant women with low-risk pregnancies will be randomly assigned to receive either standard pren…

This study looks at how doctors trust artificial intelligence (AI) when estimating a baby's weight during pregnancy. About 308 clinicians will review ultrasound cases and compare AI-based estimates with traditional methods. Some doctors will also see how certain the AI is about i…

This study will test if listening to binaural beats (special sounds that can calm the brain) can lower the amount of anxiety medication needed during a C-section done with spinal anesthesia. About 200 pregnant women having planned C-sections will be randomly assigned to listen to…

This study will test if a mobile app called MI MOM helps improve pregnancy and postpartum health. About 500 pregnant women on Medicaid will either use the app or receive standard care. The app provides health information, text messages, and optional support from a community healt…

This study looks at the reproductive health experiences of over 1,100 female Canadian Armed Forces members and veterans. It covers contraception, pregnancy, infertility, and pelvic floor issues, plus access to care and career effects. The goal is to gather information through sur…

This study looks at better ways to find tuberculosis (TB) in pregnant and postpartum women in Guinea-Bissau. Researchers will test a simple symptom checklist, a stool test, and AI-powered chest X-rays to see if these tools can catch more TB cases. About 720 pregnant women will ta…

This study looks at whether a video call (teleconsultation) works as well as an in-person visit for checking pregnant women before they receive anesthesia during delivery. About 250 first-time mothers will take part. The goal is to see if the quality and safety of the anesthesia …

This study tests whether a real-time AI dashboard can help doctors make better decisions during labor for first-time mothers. About 400 women will be randomly assigned to have their care guided by the AI tool or to receive standard care. The main goal is to see if the AI can safe…

This study looks at how sleep, activity, and meal timing in early pregnancy relate to blood sugar patterns and the risk of gestational diabetes. About 140 pregnant women without diabetes will wear monitors and use a food app to track their habits. The goal is to see if these beha…