One pill to prevent HIV and pregnancy? new study tests simpler option for women

NCT ID NCT07288190

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a single daily pill that combines HIV prevention (PrEP) and birth control is easier for women to take consistently than taking two separate pills. About 300 women without HIV will try both approaches in a crossover design, and researchers will measure adherence through blood tests. The goal is to see if a simpler regimen improves daily use.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

DPP (single pill combining FTC/TDF and ethinyl estradiol/levonorgestrel)

What this could lead to

If it works, this could make it simpler for women to prevent both HIV and pregnancy with just one daily pill.

What could go wrong

This is a small, early-phase study (Phase 2) with only 300 participants, so results may not apply to everyone. It focuses on adherence, not on actual HIV or pregnancy prevention.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Eswatini Prevention Center CRS

    Mbabane, Eswatini

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • MU-JHU Research Collaboration (MUJHU CARE LTD) CRS

    Kampala, Uganda

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Spilhaus CRS

    Harare, Zimbabwe

    Contact Phone: •••-•••-•••• Email: •••••@•••••