PREGNANCY

This study is testing whether adding a specific peptide called cpFT to the liquid where eggs and embryos grow during IVF (ICSI procedure) can increase the chance of having a live baby. It involves 366 couples where the woman is under 37 years old. Participants are randomly assign…

This study is testing whether delivering healthy meals to the homes of low-income Black pregnant women helps them eat better and manage their weight and blood pressure during pregnancy. Researchers will provide 10 meals per week to about 17 participants and compare their health o…

This small pilot study is testing whether a 12-week lifestyle program focused on walking and physical activity can help pregnant women reduce or stop using cannabis. The study will enroll 50 women who are between 12 and 25 weeks pregnant, who currently use cannabis but want to st…

This study is testing whether group prenatal care is better than traditional one-on-one visits for pregnant women with type 2 or gestational diabetes. It will compare how well each approach helps control blood sugar during pregnancy and manage weight after giving birth. The goal …

This study is testing whether a smartphone app can help pregnant women manage their blood sugar and gain a healthy amount of weight. Researchers will enroll 160 first-time mothers to use the app and track their progress. The goal is to see if digital tools can support better heal…

This study is testing a coordinated care program designed to help pregnant and postpartum women with opioid addiction in rural, low-resource areas. The program aims to help women start and stay on addiction medication, reduce overdose risk, and lower the chance of children being …

This study aims to find the safest way to prevent tuberculosis (TB) in pregnant people living with HIV. Researchers are comparing two different dosing schedules of TB prevention drugs to see how well they work with standard HIV medications and how safe they are for both the pregn…

This study aimed to test if a non-invasive finger monitor (ClearSight™) works as well as a heart ultrasound for checking a pregnant woman's fluid needs during late pregnancy. The goal was to see if the finger monitor could reliably tell doctors when a patient would benefit from e…

This VA study aims to improve how 20 VA medical centers provide virtual health programs to women Veterans. It's testing two different support strategies to help these facilities successfully offer proven programs for preventing heart disease, diabetes, and depression. The goal is…

This study is testing whether a supervised exercise program during the second and third trimesters of pregnancy can improve health for both mothers and their babies. Researchers will enroll 64 first-time pregnant women and randomly assign them to either follow the exercise progra…

This study is testing whether a brief home visitation program can help pregnant women and new mothers. It aims to help them connect to community resources, feel more confident about their health, and reduce stress. The program is delivered by trained non-nurse visitors and is bei…

This study is testing the safety and immune response of the MVA-BN mpox vaccine in pregnant and recently delivered women in the Democratic Republic of the Congo, where mpox is a risk. It will enroll 359 women to receive two vaccine doses either during pregnancy or right after giv…

This study is testing whether taking specific B-vitamins (riboflavin and folate) can help prevent high blood pressure during pregnancy for women who have a particular genetic trait. Researchers are enrolling 2,250 pregnant women in their first trimester to see if this personalize…

This study is testing whether using a virtual reality (VR) relaxation app can help reduce nausea and vomiting, improve sleep, and increase overall comfort for pregnant women. Researchers will compare 90 pregnant women who use the VR app daily to a group receiving standard care. T…

This study is testing whether giving calcium carbonate, a common over-the-counter supplement, to pregnant people during labor induction can make the process better. Researchers want to see if it shortens the time needed for induction medicine, lowers the chance of a difficult lab…

This study is testing whether a specific meditation technique called ThetaHealing can help first-time mothers manage labor pain and reduce fear during childbirth. Researchers will provide meditation training to some participants before birth and measure their pain and brain activ…

This study is testing whether a special mindfulness-based childbirth and parenting class is better than a standard class at reducing anxiety in pregnant women. It will enroll 60 pregnant women with elevated anxiety and randomly assign them to one of the two class types. The resea…

This study is testing whether eating date fruit can help reduce vomiting and fatigue from morning sickness in the first three months of pregnancy. Researchers are comparing the effects of dates against a common anti-nausea medication and a diet-only approach in 40 pregnant partic…

This study is testing two non-drug methods to help reduce anxiety in pregnant women. Researchers are comparing laughter yoga sessions and a tapping technique called EFT against a control group to see which is more effective. The goal is to find safe, accessible ways to improve me…

This study is observing whether using virtual reality (VR) headsets during a cesarean section can help reduce anxiety and symptoms of postpartum depression. It involves 98 pregnant women having planned C-sections, with half using VR and half receiving standard care. Researchers a…

This study aims to find out if a drug called sugammadex, used to reverse muscle relaxants after surgery, can cross the human placenta and reach a developing fetus. Researchers will use donated placentas from healthy pregnancies in a lab model to measure drug transfer. The goal is…

This study aims to understand why preterm births and stillbirths happen in Zambia. Researchers will follow 9,000 pregnant women and their babies for a year after birth, collecting health information and biological samples. The goal is to discover the underlying causes to help dev…

This study is testing a special education program designed to help first-time mothers with breastfeeding. The program combines information about breastfeeding with motivation techniques and relaxation methods from 'hypnobreastfeeding.' Researchers want to see if this approach imp…

This study is creating a collection of biological samples and health data to help researchers better understand infertility, gynecological disorders, and pregnancy-related conditions. It involves 3,000 participants, including both people affected by these conditions and healthy v…

This study aims to find out if the constipation medicine prucalopride is safe for use during pregnancy. Researchers will look at existing health insurance records of about 100 pregnant women with constipation, comparing those who took prucalopride to those who took other medicine…

This study aims to learn how the body's response to insulin changes before, during, and after pregnancy in people with Type 1 Diabetes. Researchers will analyze existing data from 100 participants who used specific glucose monitors and insulin pumps during a past pregnancy. The g…

This study is testing if a short educational video can help pregnant women better understand the anesthesia process for a scheduled C-section. Researchers want to see if watching the video before meeting the anesthesiologist improves how informed patients feel about their choices…

This study gathered 25 expert doctors to create clear, safe skin care guidelines for pregnant women. They agreed on which ingredients and products are safe to use and which should be avoided to protect both mother and baby. The guidelines help doctors recommend gentle cleansers, …

This study looks at existing health records to understand if taking the weight-loss medication Wegovy during pregnancy affects the health of mothers and babies. Researchers will compare about 1,100 pregnancies where women took Wegovy to pregnancies where they didn't. The goal is …

This study aims to understand how a mother's use of substances like cocaine, alcohol, marijuana, or cigarettes during pregnancy might affect her bond with her baby and the baby's early brain development. Researchers are inviting mothers who have or have not used these substances …

This study aimed to test whether MRI scans could provide better information about how the placenta works during pregnancy, especially when a baby isn't growing properly. Researchers planned to compare MRI measurements of blood flow and structure in placentas from high-risk and lo…

This study aims to understand how a pregnant person's stress and mental health affect their body's ability to process blood sugar. Researchers are looking at medical records and following 150 pregnant volunteers to see if stress helps explain why some people develop gestational d…

This study is collecting information about pregnancy outcomes for women who take Wegovy (semaglutide) for weight management. Researchers will compare about 728 pregnant women who take Wegovy with similar women who don't take the medication. They'll track birth outcomes, complicat…

This study gathers expert opinions to create clear guidelines for using vitamins, minerals, and other supplements during pregnancy. A panel of experienced pregnancy doctors and nutrition specialists will review evidence and vote on recommendations through multiple rounds of discu…

This study aimed to test whether training obstetric providers to counsel pregnant patients about workplace rights and accommodations would lead to better outcomes. The trial planned to compare trained providers against usual care, measuring how often work-related counseling was d…