Mpox vaccine trial for pregnant women launches in congo
NCT ID NCT06844500
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This Phase 3 trial is testing the safety and immune response of the MVA-BN mpox vaccine in 359 pregnant and postpartum women in the Democratic Republic of the Congo. Some women receive the vaccine during pregnancy, others right after giving birth, and a small group gets it as an emergency shot after mpox exposure. The study also checks how much protection passes to their babies through the placenta and breast milk, and follows infants for over a year.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
MVA-BN vaccine (Modified Vaccinia Ankara-Bavarian Nordic)
What this could lead to
If successful, this could show that the MVA-BN mpox vaccine is safe and effective for pregnant women and their newborns, helping protect them from mpox in high-risk areas.
What could go wrong
This is an open-label trial with no placebo group, so results may be less definitive. The study is also limited to one region in the DRC, so findings may not apply everywhere.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Boende Hôpital Général de Référence
Boende, Province de La Tshuapa, Democratic Republic of the Congo