OSTEOARTHRITIS

This study is tracking a specific knee replacement implant over 10 years to see how well it reduces pain, improves mobility, and lasts inside the body. It involves about 300 adults with severe knee arthritis who receive the implant. Researchers will check in regularly using X-ray…

This study is following 240 people for 10 years after they receive a specific brand of personalized knee replacement. Researchers want to see how safe the implant is and how well it relieves pain and improves movement for people with severe knee arthritis. The study tracks patien…

This study is testing whether giving a single high dose of vitamin D before hip or knee replacement surgery to patients with low levels can help reduce complications like infections. It involves 200 adults with osteoarthritis and low vitamin D. Researchers want to see if this sim…

This study is tracking how well a new type of shoulder replacement implant works over time. It follows 152 patients with severe shoulder arthritis who received the implant, checking their pain, movement, and quality of life for up to 10 years after surgery. The main goal is to co…

This study is testing the safety and performance of a new hip replacement system called CATALYSTEM. It involves 119 adults with severe hip damage from conditions like arthritis. Researchers will follow patients for 10 years to see how well the implant holds up and improves their …

This study is tracking the safety and performance of a specialized metal plate used to fix broken shoulders. It will follow 135 adults who get this plate after a shoulder fracture to see how well they heal, how much their shoulder moves, and if they need another surgery. The main…

This study is testing how well a new knee replacement system works for patients who need a second or revision surgery. It's for people whose first knee replacement failed or who have severe arthritis, deformity, or pain. Researchers will track how well the new implant improves pa…

This study is following people who received a specific type of knee replacement, called the Persona implant, to see how well it works and how long it lasts over ten years. It includes adults with severe knee pain from conditions like arthritis who need a total knee replacement. R…

This study is observing how well a new hip replacement system works and how safe it is for patients with severe hip arthritis or similar conditions. It will follow 230 patients who receive the implant to see how long it lasts and how much it improves their pain and mobility. The …

This study is comparing two ways to perform total shoulder replacement surgery for people with severe arthritis. About 120 patients will be randomly assigned to get either the traditional surgery or a newer 'rotator cuff sparing' technique that avoids cutting a major shoulder ten…

This study is tracking how well Persona brand knee replacement implants work and how long they last in people with severe knee arthritis. It follows 777 adults who get the implant for severe pain and disability, checking their pain, function, and quality of life for up to 10 year…

This study compares two common treatments for people with knee arthritis and a torn meniscus (a piece of cartilage in the knee). Researchers want to know if surgery or a structured physical therapy program works better to improve knee function and reduce pain. About 350 adults wi…

This study is tracking how well a specific type of shoulder replacement implant works over time. It involves 200 adults with severe shoulder problems like arthritis or complex fractures who need a 'reverse' shoulder replacement. Researchers will follow patients to see how long th…

This study aims to see if a newer, all-plastic part for knee replacements stays in place as well as the older style that has a metal backing. Researchers will track 60 patients with severe knee arthritis for two years using special X-rays to measure tiny movements of the implant.…

This study compares two types of knee replacement implants—one that uses bone cement and one that doesn't—to see which provides better long-term results. Researchers will follow 300 patients with severe knee arthritis for up to 5 years after surgery, measuring pain levels, knee f…

This early-stage study aimed to test the safety and feasibility of a single injection of a patient's own processed fat tissue into the knee to treat arthritis that developed after a significant injury. The goal was to see if this approach could help younger, active adults with pe…

This study is evaluating a new type of cementless knee replacement implant for people with severe osteoarthritis. It aims to see how well the implant improves daily activities, reduces pain, and holds up over time. Researchers will follow 540 patients for up to five years after s…

This study aimed to test a new, non-surgical procedure for people with chronic knee pain from arthritis who are not candidates for surgery. Doctors planned to inject a medication called doxycycline into tiny blood vessels around the knee to try to reduce pain. The goal was to see…

This study is testing whether a deep-heat therapy called short wave diathermy can help people with hand osteoarthritis. It will compare the therapy plus hand exercises against sham (fake) therapy plus exercises in 36 participants. The main goal is to see if the treatment reduces …

This study is testing whether special gloves can help reduce pain and improve hand function for people with hand osteoarthritis. The gloves are embedded with a material that emits gentle energy and negative ions, which researchers believe may increase blood flow and reduce inflam…

This study is testing whether capsules containing a concentrated turmeric extract can reduce pain and inflammation in adults with knee osteoarthritis. Researchers will compare the turmeric capsules to a placebo (a dummy pill with no active ingredient) over three weeks. The main g…

This study tested whether two types of non-invasive brain stimulation could reduce pain and improve daily function for people with chronic knee osteoarthritis. Researchers compared real stimulation to a fake (sham) treatment in 64 participants to see if it lowered their pain scor…

This study aims to collect and analyze fluid from the shoulder, hip, and knee joints to find biological markers that signal the start or progression of osteoarthritis. Researchers will enroll 149 adults who are already scheduled for joint surgery to build a collection of these fl…

This study aims to understand how best to measure pain and physical function in people with knee osteoarthritis. Researchers will enroll 100 participants with moderate knee arthritis to compare different questionnaires and physical tests. The goal is to gather information that co…

This study is creating a national registry to track 30,000 patients who have hip or knee replacement surgery for osteoarthritis. Researchers will collect information about patients' pain, function, and complications before and after surgery to identify what works best. The goal i…

This study looks at whether a new payment system called 'bundled payments' improves the quality of care while reducing costs. Researchers are analyzing Medicare data from 440 healthcare providers treating conditions like joint replacements, pneumonia, and COPD. The goal is to see…

This study aims to collect information on how osteoarthritis patients feel after receiving standard low-dose radiation therapy for joint pain. Researchers will follow 40 patients to track their pain levels, joint function, and quality of life over time. The goal is to better unde…