OSTEOARTHRITIS
Clinical trials for OSTEOARTHRITIS explained in plain language.
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Knee osteoarthritis drug trial halted midway
Disease control TerminatedThis study tested an experimental drug called LNA043, given as a shot into the knee, to see if it could slow down cartilage loss and reduce pain in people with knee osteoarthritis. The trial planned to enroll 576 adults aged 40 to 75 with knee osteoarthritis. The study was termin…
Matched conditions: OSTEOARTHRITIS
Phase: PHASE2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated May 12, 2026 13:43 UTC
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Tiny nerve zapper eases knee pain without surgery?
Symptom relief TerminatedThis study tested a temporary device that stimulates nerves around the knee to relieve chronic pain from osteoarthritis. Twelve adults with knee pain received the treatment, and researchers measured changes in pain intensity and quality of life. The goal was to see if this non-su…
Matched conditions: OSTEOARTHRITIS
Sponsor: Wake Forest University Health Sciences • Aim: Symptom relief
Last updated May 17, 2026 02:07 UTC
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Laser light tested to ease hand arthritis pain in military members
Symptom relief TerminatedThis study looked at whether low level laser therapy (LLLT) can reduce pain and improve hand function in people with hand osteoarthritis. About 83 military members and their families were to receive either real LLLT or a sham treatment once a week for six weeks. The study was ter…
Matched conditions: OSTEOARTHRITIS
Phase: NA • Sponsor: David Moss • Aim: Symptom relief
Last updated May 17, 2026 02:03 UTC
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Knee surgery pain study: does an extra nerve block help?
Symptom relief TerminatedThis study looked at whether adding a nerve block (adductor canal block) to standard pain injections around the knee could reduce pain after total knee replacement. 93 adults having their first knee replacement for osteoarthritis took part. The goal was to find the best way to ma…
Matched conditions: OSTEOARTHRITIS
Phase: PHASE2, PHASE3 • Sponsor: OrthoCarolina Research Institute, Inc. • Aim: Symptom relief
Last updated May 17, 2026 02:01 UTC
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Hip implant migration study halted early
Knowledge-focused TerminatedThis study aimed to measure how much a specific hip implant (the Pinnacle Acetabular Shell) moves in the bone over two years after hip replacement surgery. Researchers used a special X-ray technique called RSA to track implant movement. The study included 100 people needing hip r…
Matched conditions: OSTEOARTHRITIS
Phase: NA • Sponsor: DePuy Orthopaedics • Aim: Knowledge-focused
Last updated May 17, 2026 02:08 UTC
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Custom knee implants fail to prove superiority in halted study
Knowledge-focused TerminatedThis study aimed to see if a custom-made knee replacement (ConforMIS iTotal) helps patients move better than a standard off-the-shelf knee replacement. Researchers planned to enroll 215 adults with osteoarthritis who needed knee surgery. The study was stopped early, so results ar…
Matched conditions: OSTEOARTHRITIS
Phase: NA • Sponsor: Restor3D • Aim: Knowledge-focused
Last updated Apr 26, 2026 20:00 UTC