OSTEOARTHRITIS

This study aims to see if two common types of diabetes medications can help control osteoarthritis symptoms in people who have both type 2 diabetes and arthritis. It will compare the effects of GLP-1 and SGLT2 inhibitor drugs against standard care on joint pain, stiffness, and ph…

This early-stage study is testing a new treatment called XytriX, which is made from umbilical cord stem cells, for knee osteoarthritis. It will involve about 50 adults with knee arthritis confirmed by X-ray. The main goal is to see if the injection is safe and if it helps reduce …

This study aims to see if a virtual, team-based lifestyle program works as well as traditional in-person physiotherapy for managing chronic pain in rural adults. It will enroll 354 people with conditions like back pain, knee pain, or hip pain who also have lifestyle risks like be…

This study is testing whether using ultrasound to deliver bee venom through the skin can help manage pain and improve mobility in people with knee osteoarthritis. Thirty adults with knee arthritis will be randomly assigned to receive either the bee venom treatment or a placebo ge…

This study is testing if a supervised ketogenic diet (a very low-carb, high-fat eating plan) can help reduce pain and improve thinking in older adults who have both osteoarthritis and mild memory problems. Ten participants will follow the diet, and researchers will check their pa…

This study aims to see if a new tablet called Laybon is as good as an existing tablet called Layla at reducing knee pain from osteoarthritis. About 172 adults with knee osteoarthritis will take one of the tablets for 8 weeks. The main goal is to measure changes in knee pain durin…

This study is testing a gel called Sensovisc, which is injected directly into the hip joint. The goal is to see if it is safe and can help reduce pain and improve movement for people with hip osteoarthritis. Researchers will enroll 25 adults with moderate hip arthritis to measure…

This study is testing whether a daily drink made from freeze-dried Rosa roxburghii fruit powder can help people recover better after knee replacement surgery. The researchers want to see if the powder reduces inflammation, lowers oxidative stress, and improves knee function and p…

This study is testing a new injection called ALT001 to see if it can safely reduce pain and improve movement in people with knee osteoarthritis. 30 participants will receive either a placebo or one of two doses of ALT001, injected into the knee every two weeks for six treatments.…

This study aims to understand how patients decide whether to get imaging tests like X-rays or MRIs for common joint, tendon, and nerve conditions. Researchers will compare how a structured conversation versus basic written information affects patients' desire for testing and thei…

This study aims to better understand early knee osteoarthritis by collecting small tissue samples from the joint lining. Researchers will analyze these samples from 30 patients to look for patterns linked to pain and disease progression. The goal is to gather knowledge that could…

This study aims to understand how different immune cells in the blood are related to disease activity in people with various autoimmune conditions. Researchers will analyze blood samples from 500 participants, including people with diseases like lupus and rheumatoid arthritis, as…

This study aims to learn more about severe jaw joint disorders, which can cause pain and lock the jaw shut. Researchers will observe 20 patients undergoing surgery, analyzing their joint tissue and tracking their pain and jaw movement for two years. The goal is to find patterns t…