Could a rose fruit powder ease pain after knee replacement?

NCT ID NCT07395856

Not yet recruiting Symptom relief Sponsor: Shuguang Gao Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a powder made from Rosa roxburghii (a type of rose fruit) can help people recover after total knee replacement surgery for osteoarthritis. 184 participants will take either the supplement or a placebo daily for 30 days after surgery. Researchers will measure inflammation, oxidative stress, pain, and knee function to see if the supplement improves recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Rosa roxburghii (rose fruit) juice freeze-dried powder
What this could lead to: If it works, this could point toward a natural supplement to help people recover faster and with less pain after knee replacement surgery.
What could go wrong: This is a small, early-stage trial with only 184 participants, and it uses a dietary supplement, not a drug. The results may not be strong enough to recommend it widely, and the placebo effect could play a role.

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OSTEOARTHRITIS

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