Blood test may predict need for hip revision surgery

NCT ID NCT02208271

Terminated Diagnosis Sponsor: OrthoCarolina Research Institute, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aimed to develop a biomarker test using blood or joint fluid to detect tissue damage (necrosis) caused by metal-on-metal hip implants. Researchers planned to enroll 174 patients, including those needing revision surgery and a control group. The goal was to see if the test could accurately identify who needs surgery, but the study was terminated early.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could provide a simple test to help doctors decide when revision surgery is needed for metal-on-metal hip implants.
What could go wrong: The study was terminated early, so results are limited. The test is still experimental and not yet proven to work in routine care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

arthritic joint disease osteoarthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ARTHRITIS, FAILURE OF TOTAL HIP

Contacts and locations

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Locations

OrthoCarolina

Charlotte, North Carolina, 28207, United States

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