Could simple home exercises be the key to better knee health?
NCT ID NCT07804212
First seen Sep 04, 2026 · Last updated Sep 04, 2026
Summary
This trial tests whether a home-based strength training program combined with self-management education can reduce symptoms and improve quality of life for people with knee osteoarthritis. Participants aged 45 and older are randomly assigned to either the exercise and education program or standard care. Researchers measure changes in knee symptoms, sleep quality, emotional well-being, and quality of life over three months.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- A structured home-based strength training program combined with self-management education
- What this could lead to
- If it works, this could offer a drug-free way to reduce knee pain and stiffness, and improve sleep and mood for people with knee osteoarthritis.
- What could go wrong
- This is a small, early-stage trial without blinding, so results may be influenced by participants' expectations. The program requires consistent home exercise, and not everyone may benefit.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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May 2027
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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45 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 45 or older * Diagnosed with symptomatic knee osteoarthritis by a physician * Normal hearing and able to communicate effectively Exclusion Criteria: * Severe inflammatory arthritis * Pending or previous unilateral or bilateral total knee replacement * Contraindications to exercise therapy * Received physical therapy or knee injections in the past month * Psychiatric or cognitive impairments
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Fooyin University
Kaohsiung City, Taiwan (r.o.c.), 831301, Taiwan
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