Fat cell knee injection trial for Post-Trauma arthritis pulled before start
NCT ID NCT05515523
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot trial aimed to test the safety and feasibility of a single injection of a patient's own fat-derived cells (stromal vascular fraction) into the knee for post-traumatic osteoarthritis. It was designed for adults aged 18–45 with a history of knee injury. However, the study was withdrawn before enrolling any participants, so no results are available.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- stromal vascular fraction (SVF) cells from the patient's own fat tissue
- What this could lead to
- If successful, this approach could point toward a way to reduce pain and improve knee function after injury-related arthritis, possibly delaying or avoiding joint replacement.
- What could go wrong
- This was a very early pilot trial (Phase 1) that was withdrawn before any participants were enrolled, so no safety or effectiveness data exist. The approach is still highly experimental and unproven.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Wake Forest University Health Sciences
Winston-Salem, North Carolina, 27157, United States
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