New knee implant aims to get patients moving again
NCT ID NCT05197036
First seen Jun 26, 2026 · Last updated Aug 12, 2026 · Updated 3 times
Summary
This study follows 299 people who received the Smith+Nephew Porous Total Knee System, a titanium knee replacement for severe arthritis. The goal is to see if the implant reduces pain, improves movement, and lasts at least two years without needing revision surgery. Participants are either getting the implant now or have already received it in the past year.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Total Knee Arthroplasty (surgical knee replacement with titanium prostheses)
- What this could lead to
- If successful, this could confirm that the Smith+Nephew Porous Total Knee System provides lasting pain relief and improved mobility for people with severe knee arthritis.
- What could go wrong
- This is an observational follow-up study, not a randomized controlled trial, so results may not prove superiority over other implants. Some patients may still experience complications like implant loosening or infection.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Columbia University
New York, New York, 10032, United States
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Concordia Joint Replacement Group
Winnipeg, Manitoba, R2K2M9, Canada
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Duke Health
Morrisville, North Carolina, 27560, United States
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Emory Orthopaedics and Spine Hospital
Atlanta, Georgia, 30084, United States
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Erlanger Health
Chattanooga, Tennessee, 37403, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Medical Center Leeuwarden
Leeuwarden, Leeuwarden, 8934, Netherlands
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Medical University of South Carolina
Charleston, South Carolina, 29425, United States
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NYU Langone Health Orthopedic Hospital
New York, New York, 10016, United States
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Oregon Health & Science University
Portland, Oregon, 97239, United States
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Sint Maartenskliniek
Ubbergen, Ubbergen,, 6574, Netherlands
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St George and Sutherland Centre for Clinical Orthopaedic Research
Sydney, New South Wales, Australia
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Syracuse Orthopedic Specialists
East Syracuse, New York, 13057, United States
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The Avenue Hospital
Windsor, Victoria, 3181, Australia
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The Core Institute
Novi, Michigan, 48374, United States
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UTHealth
Houston, Texas, 77401, United States
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Umeå University Hospital
Umeå, Umeå, 90737, Sweden
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University of Wisconsin
Madison, Wisconsin, 52718, United States
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