One vitamin d pill before surgery may cut infection risk
NCT ID NCT07006714
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests whether giving a single high-dose vitamin D pill to patients with low vitamin D levels before hip or knee replacement surgery can reduce complications like infection. About 200 adults with osteoarthritis and vitamin D deficiency will receive 300,000 IU of vitamin D3 before surgery. Researchers will track infections, hospital stay length, and readmission rates.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Vitamin D3
What this could lead to
If it works, this could show that correcting vitamin D deficiency before joint replacement surgery lowers the risk of infection and other complications.
What could go wrong
This is a small, single-center study with only 200 participants. The high dose may cause side effects, and results may not apply to all patients.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Miami
Miami, Florida, 33136, United States