One vitamin d pill before surgery may cut infection risk
NCT ID NCT07006714
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests whether giving a single high-dose vitamin D pill to patients with low vitamin D levels before hip or knee replacement surgery can reduce complications like infection. About 200 adults with osteoarthritis and vitamin D deficiency will receive 300,000 IU of vitamin D3 before surgery. Researchers will track infections, hospital stay length, and readmission rates.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Vitamin D3
- What this could lead to
- If it works, this could show that correcting vitamin D deficiency before joint replacement surgery lowers the risk of infection and other complications.
- What could go wrong
- This is a small, single-center study with only 200 participants. The high dose may cause side effects, and results may not apply to all patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Miami
Miami, Florida, 33136, United States
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