MIGRAINE

This study looked at the long-term safety of eptinezumab, a medicine given as an infusion to prevent migraines. It included 160 Japanese adults who had already completed a previous study. The main goal was to see if the drug was safe and tolerable over 60 weeks of treatment.

This study looked at the long-term safety and effectiveness of a monthly injection called fremanezumab for preventing migraine in children aged 6 to 17. Over 500 participants received the drug for up to 84 months. The goal was to see if it is safe and helps reduce migraine days. …

This study tested whether adding eptinezumab (a migraine prevention drug) to a brief educational program helps adults with both migraine and medication overuse headache. Over 600 participants were followed to see if the drug reduced monthly migraine days, headache days, and the n…

This study tested a drug called fremanezumab, given as a shot under the skin once a month or once every three months, to prevent migraines in 365 Chinese adults. The main goal was to see if it reduced the number of migraine days per month compared to a placebo. The drug is design…

This study looked at the safety of taking rimegepant every day to prevent episodic migraines. 441 adults with a history of migraines took the pill daily and were monitored for side effects. The main goal was to see how well people tolerated the medication over time, not to measur…

This study tested a drug called eptinezumab to see if it could prevent migraines in people with chronic migraine. Nearly 1,000 adults with at least 8 migraine days per month took part. The main goal was to see if the drug reduced the number of monthly migraine days compared to a …

This study tested whether taking rimegepant daily or every other day can prevent migraines in people with episodic migraine (4-14 migraine days per month). Over 1400 adults participated, and researchers measured how much migraine days decreased over 12 weeks compared to a placebo…

This study tested a home-based biofeedback app called Cerebri for preventing migraine attacks in adults with episodic migraine. 279 participants either used the app for 10 minutes daily or joined a wait-list group. Researchers compared how much migraine days decreased in each gro…

This study tested whether a pill called rimegepant can help prevent migraines in Chinese adults. About 787 people with a history of migraines took the medicine every other day for 12 weeks. The main goal was to see if it reduced the number of migraine days per month compared to a…

This study tested whether the drug rimegepant can help prevent migraines in Japanese adults. About 496 people with a history of migraines took either the drug or a placebo for 12 weeks. The main goal was to see if the drug reduced the number of migraine days per month compared to…

This study looked at whether prayer can change how people with migraines feel pain, anxiety, and depression. About 100 adults, half with migraines and half without, took part. They compared praying to reading a text to see if prayer raised pain tolerance and improved mood.

This early-stage study looked at whether a new drug called Lu AG09222 is safe to take together with the migraine medication ubrogepant. 43 adults with migraine received ubrogepant pills plus an injection of either Lu AG09222 or a placebo. The main goal was to track any side effec…

This study followed 226 adults in Israel who were prescribed ubrogepant or atogepant for their migraines. Researchers wanted to see how satisfied people were with these drugs in real life, not just in a lab. Participants took the medicine as their doctor ordered and reported thei…

This study tested a biofeedback device that uses muscle sensors and a smartphone app to help people with chronic low back pain, pain after breast surgery, or migraines learn to relax tense muscles. About 330 adults were randomly assigned to use the device or receive usual care. T…

This study tested three types of medication—blood thinners, anti-clotting drugs, and standard migraine treatments—to see which best reduces migraine attacks in people who also have a small hole in the heart (PFO). About 1,000 adults with frequent migraines took part. The goal was…

This study tested whether injecting a small amount of lidocaine (a numbing medicine) into a specific acupuncture point on the back of the head can safely reduce migraine attacks. Thirty adults with migraines received either weekly lidocaine injections for four weeks or a daily pr…

This study tested a new migraine medication called AXS-07 (a combination of meloxicam and rizatriptan) in 100 adults whose migraines did not respond well to oral CGRP inhibitors. The goal was to see if the drug could relieve headache pain and the most bothersome symptom without n…

This study tested a new medication called BHV-2100 to see if it can safely and quickly stop migraine pain and other symptoms like nausea or sensitivity to light. About 647 people with migraines took either the drug or a placebo. The main goal was to see how many were pain-free an…

This study tested a 12-week telehealth program for people with migraine. Twenty participants used a mobile app headache diary, an online manual, and had virtual sessions with a coach. The goal was to see if the program was easy to use and if it helped improve quality of life.

This study looked at how well and how safely lasmiditan works for treating migraines quickly. About 100 adults with migraine (with or without aura) took the drug during an attack. Researchers measured if headache pain went away within 2 hours and tracked any side effects.

This study looked at how a nerve stimulation device (like a gentle zap on the neck) combined with stress-reduction training affects the brains of people with migraine. Researchers compared brain scans and inflammation levels in 193 adults with migraine and healthy volunteers. The…

This study looked at how well the migraine medication Rimegepant works in real-world settings. 173 adults with migraine took the drug as needed for attacks or prevention. Researchers tracked pain relief at various times and monitored safety over the long term.

This study tested a new drug called MTX101, given as a tablet under the tongue, for quickly treating migraine headaches in adults. 78 people with migraines took either the drug or a placebo during separate attacks to see if it reduced pain and the need for rescue medication. The …

This study tested a drug called rimegepant for quickly treating migraine headaches in adults who cannot use triptans (common migraine drugs) due to side effects, lack of effectiveness, or heart risks. Over 800 participants took either rimegepant or a placebo and reported their pa…

This study looked at whether giving children with migraines just intravenous (IV) fluids (salt water) in the emergency department can help reduce their headache pain. 46 children took part. The goal was to see if fluids alone, without extra medicine, could ease symptoms.

This study tested whether foot reflexology—a type of focused foot massage—could help people with migraines feel less pain and fatigue and improve their daily life. 78 adults with migraines took part; half received 10 reflexology sessions over 5 weeks, while the other half continu…

This study looked at whether combining posture correction with a gentle spinal technique (sustained natural apophyseal glides) could reduce migraine severity, disability, and improve quality of life. 44 adults with episodic migraine took part. The goal was to see if these non-dru…

This study looked at how well a wearable device that sends gentle electrical signals works for treating migraines in US veterans. Over 460 veterans used the device during a migraine attack and reported their pain levels two hours later. The main goal was to see if they still need…

This study checked if using the Nerivio device for migraine headaches during pregnancy and up to 3 months after birth is safe. It compared 145 women with migraine who used Nerivio to those who did not, looking at baby's birth weight, delivery timing, and miscarriage rates. The go…

This study tested a new oral medicine called AXS-07 for quickly stopping migraine headaches in adults. 302 people with migraines took either the study drug or a placebo when their headache started. The goal was to see if the drug could provide pain relief and eliminate the most b…

This study tested the drug erenumab in 512 adults with high-frequency episodic migraine (7 to 14 migraine days per month) who had already tried at least one other preventive treatment without success. The main goal was to see if erenumab could reduce the total hours of moderate-t…

This study tested a new wearable device that uses gentle electrical pulses on the head and neck to relieve migraine pain. 160 adults with migraines used the device during attacks, and researchers compared real stimulation to a sham (fake) treatment. The goal was to see if the dev…

This study tested a device called Mi-Helper that cools the inside of the nose to treat migraines at home. 156 adults with migraines used either the real device or a fake one to see if it safely reduces pain and other symptoms. The goal was to find a drug-free option for quick rel…

This study tested a drug called fremanezumab to see if it could prevent chronic migraines in children aged 6 to 17. About 292 participants received either the drug or a placebo shot. The main goal was to see if the drug reduced the number of migraine days each month over 12 weeks…

This study tested whether an AI-powered voice chatbot could help Hong Kong women with migraines track their headaches better than a traditional paper diary. 49 women used both methods for one month each. The goal was to see if the chatbot led to more complete, timely, and accurat…

This study tested a wearable device called Nerivio for treating migraine headaches in children ages 6 to 11. The device uses gentle electrical pulses to ease pain without medication. Researchers checked how safe it was and whether it helped reduce headache pain within two hours.

This study tested a monthly injection called erenumab in 557 Asian adults with chronic migraine (15+ headache days per month). Over 12 weeks, the drug reduced the number of migraine days compared to a placebo. The goal was to ease symptoms and improve daily life, not to cure migr…

This study compared inhaling isopropyl alcohol (rubbing alcohol) vapor to eucalyptus scent for treating nausea during migraines. 21 adults with frequent migraines took part. Researchers measured how much nausea changed and any side effects.

This study tested whether the drug erenumab can help prevent migraines in children aged 6 to 17 with chronic migraine (15+ headache days per month). About 284 participants received either erenumab or a placebo. The main goal was to see if the drug reduced the number of monthly mi…

This study tested a type of mindfulness training called Acceptance and Commitment Therapy (ACT) for women who have migraines 4 to 14 days per month. Researchers wanted to see if it's possible to run a larger study and whether ACT can reduce how often migraines happen and how much…

This study looked at the real-world experiences of 30 migraine patients and their healthcare providers in Thailand using eptinezumab, a preventive migraine infusion. Through interviews and questionnaires over 6 months, researchers aimed to identify what makes it easier or harder …

This study looked at how migraine affects neck stability, sense of position, and body awareness. Researchers compared 64 adults with migraine to healthy volunteers using questionnaires and physical tests. The goal was to see if these factors differ between groups and how they rel…

This study looked at whether a strong sensitivity to smells (called osmophobia) can help tell the difference between migraine and tension-type headaches. Over 200 adults with either condition tracked their headaches and smell reactions for six months. The goal was to see if osmop…

This study used machine learning to predict whether someone will have a migraine the next day. Researchers analyzed data from over 53,000 people who used the Nerivio app, including their symptoms and location. The goal was to create a model that could help people prepare for or p…

This study looked at nearly 2,000 people from the community to understand how depression, anxiety, and migraine are passed down through families. Researchers interviewed family members of all ages and collected health history to find patterns and risk factors. The goal is to use …

This study looked at survey data from over 1,300 people with migraine to compare how satisfied they were with two types of acute treatments: rimegepant (Nurtec) and triptans. Researchers measured quality of life, work productivity, and disability. The goal was to see if one treat…

This early-stage study tested a new nasal spray called PRT-064040 in 80 healthy Chinese adults to see if it is safe and how the body processes it. Participants received either a single dose or daily doses for a week. The goal was to gather safety information, not to treat migrain…

This study looked at how many infertile women have migraines and how those migraines change during IVF treatment. Researchers tracked 137 women aged 18 to 40 at a fertility center. The goal was to understand the link between hormone shifts from IVF and migraine attacks.

This study tested a single inhaled dose of prochlorperazine in 54 healthy adults to see if it is safe and how the body processes it. The goal was to gather early information, not to treat migraines. Participants were closely monitored for side effects and drug levels in the blood…