Could niacin help stop migraines? new trial tests the vitamin
NCT ID NCT05846373
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether adding niacin (a B vitamin) to a standard beta blocker could help prevent migraines. 58 adults with moderate to severe migraines took either 500 mg, 1000 mg of niacin, or a placebo daily for 12 weeks. Researchers measured changes in migraine days and pain severity.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Niacin (nicotinic acid) extended-release tablets
What this could lead to
If it works, adding niacin to a beta blocker could reduce the number of migraine days for people with moderate to severe migraines.
What could go wrong
This is a small, early-phase trial with only 58 participants. Niacin may cause side effects like flushing, and the results may not apply to everyone with migraines.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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BSMMU
Dhaka, 1000, Bangladesh