Could rubbing alcohol stop migraine nausea?

NCT ID NCT05175521

Completed Symptom relief Sponsor: HonorHealth Research Institute Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether inhaling isopropyl alcohol (rubbing alcohol) vapor can reduce nausea during a migraine attack, compared to inhaling eucalyptus scent. Twenty-one adults with frequent migraines took part. Participants inhaled the assigned scent at home when nausea started, and reported how their nausea changed over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: isopropyl alcohol vapors
What this could lead to: If it works, this could offer a quick, low-cost way to reduce nausea during a migraine attack.
What could go wrong: This was a very small trial (21 people) and the results may not apply to everyone. The effect could be due to the strong smell rather than a specific medical benefit.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

migraine disorder Nausea

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MIGRAINE

Contacts and locations

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Locations

HonorHealth Bob Bové Neuroscience Institute

Scottsdale, Arizona, 85251, United States

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