New monthly shot cuts migraine days in half for chronic sufferers?

NCT ID NCT03867201

Completed Disease control Sponsor: Novartis Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 trial tested whether a monthly injection of erenumab could reduce the number of migraine days in adults with chronic migraine (15 or more headache days per month). Over 550 Asian participants received either the drug or a placebo for 12 weeks. The main goal was to see how much migraine days dropped during the last 4 weeks of treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Erenumab (a biologic drug given by injection once a month)

What this could lead to

If it works, this could provide a new monthly treatment option to reduce the number of migraine days for people with chronic migraine.

What could go wrong

This trial is completed and showed positive results, but it only lasted 12 weeks and focused on Asian populations, so long-term effects and benefits in other groups are not yet known.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Bronchiolitis Obliterans Syndrome Headache migraine disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MIGRAINE

Contacts and locations

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Locations

Novartis Investigative Site

Beijing, Beijing Municipality, 100000, China
Novartis Investigative Site

Beijing, Beijing Municipality, 100039, China
Novartis Investigative Site

Xiamen, Fujian, 361001, China
Novartis Investigative Site

Guangzhou, Guangdong, 510000, China
Novartis Investigative Site

Shijiazhuang, Hebei, 500051, China
Novartis Investigative Site

Zhengzhou, Henan, 450052, China
Novartis Investigative Site

Jingzhou, Hubei, 434020, China
Novartis Investigative Site

Wuhan, Hubei, 430060, China
Novartis Investigative Site

Changsha, Hunan, 410003, China
Novartis Investigative Site

Changsha, Hunan, 410008, China
Novartis Investigative Site

Nanjing, Jiangsu, 210008, China
Novartis Investigative Site

Nanjing, Jiangsu, 210029, China
Novartis Investigative Site

Suzhou, Jiangsu, 215004, China
Novartis Investigative Site

Wuxi, Jiangsu, 214002, China
Novartis Investigative Site

Changchun, Jilin, 130021, China
Novartis Investigative Site

Changchun, Jilin, 130041, China
Novartis Investigative Site

Shenyang, Liaoning, 100016, China
Novartis Investigative Site

Yinchuan, Ningxia, 100039, China
Novartis Investigative Site

Jinan, Shandong, 250013, China
Novartis Investigative Site

Xian, Shanxi, 710061, China
Novartis Investigative Site

Chengdu, Sichuan, 610041, China
Novartis Investigative Site

Kunming, Yunnan, 650000, China
Novartis Investigative Site

Hangzhou, Zhejiang, 310006, China
Novartis Investigative Site

Hangzhou, Zhejiang, 310016, China
Novartis Investigative Site

Beijing, 065001, China
Novartis Investigative Site

Beijing, 100050, China
Novartis Investigative Site

Chongqing, 400016, China
Novartis Investigative Site

Qingdao, 266000, China
Novartis Investigative Site

Shanghai, 200040, China
Novartis Investigative Site

Shanghai, 200080, China
Novartis Investigative Site

Nashik, Maharashtra, 422005, India
Novartis Investigative Site

Lucknow, Uttar Pradesh, 226014, India
Novartis Investigative Site

Dehradun, Uttarakhand, 248001, India
Novartis Investigative Site

Seberang Jaya, Pulau Pinang, 13700, Malaysia
Novartis Investigative Site

Sungai Buloh, Selangor, 47000, Malaysia
Novartis Investigative Site

Kuala Terengganu, Terengganu, 20400, Malaysia
Novartis Investigative Site

Kuala Lumpur, 59100, Malaysia
Novartis Investigative Site

Manila, National Capital Region, 1000, Philippines
Novartis Investigative Site

Pasig, 1605, Philippines
Novartis Investigative Site

Singapore, 169608, Singapore
Novartis Investigative Site

Hwaseong-si, Gyeonggi-do, 18450, South Korea
Novartis Investigative Site

Seoul, Korea, 08308, South Korea
Novartis Investigative Site

Gyeonggi-do, 11765, South Korea
Novartis Investigative Site

Seoul, 03080, South Korea
Novartis Investigative Site

Seoul, 03181, South Korea
Novartis Investigative Site

Seoul, 03722, South Korea
Novartis Investigative Site

Seoul, 139-711, South Korea
Novartis Investigative Site

Chiayi City, 60002, Taiwan
Novartis Investigative Site

Taichung, 40447, Taiwan
Novartis Investigative Site

Taichung County, 411743, Taiwan
Novartis Investigative Site

Tainan, 701, Taiwan
Novartis Investigative Site

Tainan, 71004, Taiwan
Novartis Investigative Site

Taipei, 10449, Taiwan
Novartis Investigative Site

Taipei, 11217, Taiwan
Novartis Investigative Site

Taipei, 114, Taiwan
Novartis Investigative Site

Taoyuan, 33305, Taiwan
Novartis Investigative Site

Bangkok, THA, 10400, Thailand
Novartis Investigative Site

Khon Kaen, THA, 40002, Thailand
Novartis Investigative Site

Bangkok, 10330, Thailand
Novartis Investigative Site

Bangkok, 10400, Thailand
Novartis Investigative Site

Chiang Mai, 50200, Thailand
Novartis Investigative Site

Ho Chi Minh City, VNM, 700000, Vietnam
Novartis Investigative Site

Hanoi, 100000, Vietnam