New migraine pill aims to stop pain in 2 hours
NCT ID NCT04163185
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This Phase 3 trial tested a single dose of AXS-07, a combination of meloxicam and rizatriptan, for treating migraines in adults. 302 participants took either the drug or a placebo at the first sign of migraine pain. The study measured how many were pain-free and free of their most bothersome symptom after 2 hours.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
AXS-07 (a combination of meloxicam and rizatriptan)
What this could lead to
If it works, this could provide a fast-acting, single-dose option for relieving migraine pain and associated symptoms.
What could go wrong
This is a completed Phase 3 trial, but results are not yet published. The drug may not prove more effective than placebo, and side effects from the combination are possible.
Disclaimer
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the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Clinical Research Site
Birmingham, Alabama, 35205, United States
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Clinical Research Site
Birmingham, Alabama, 35216, United States
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Clinical Research Site
Mobile, Alabama, 36608, United States
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Clinical Research Site
Colton, California, 92399, United States
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Clinical Research Site
Encino, California, 91316, United States
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Clinical Research Site
Los Alamitos, California, 90720, United States
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Clinical Research Site
Los Angeles, California, 90017, United States
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Clinical Research Site
Redlands, California, 92374, United States
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Clinical Research Site
Santa Monica, California, 90404, United States
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Clinical Research Site
Spring Valley, California, 91978, United States
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Clinical Research Site
Walnut Creek, California, 94598, United States
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Clinical Research Site
Hallandale, Florida, 33009, United States
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Clinical Research Site
Jacksonville, Florida, 32256, United States
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Clinical Research Site
Lake City, Florida, 32055, United States
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Clinical Research Site
Lake Worth, Florida, 33467, United States
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Clinical Research Site
Ocoee, Florida, 34761, United States
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Clinical Research Site
Orlando, Florida, 32801, United States
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Clinical Research Site
Ormond Beach, Florida, 32174, United States
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Clinical Research Site
South Miami, Florida, 33143, United States
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Clinical Research Site
Sunrise, Florida, 33351, United States
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Clinical Research Site
Tampa, Florida, 33634, United States
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Clinical Research Site
Stockbridge, Georgia, 30281, United States
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Clinical Research Site
Evanston, Illinois, 60201, United States
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Clinical Research Site
Louisville, Kentucky, 40213, United States
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Clinical Research Site
Boston, Massachusetts, 02131, United States
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Clinical Research Site
Waltham, Massachusetts, 02451, United States
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Clinical Research Site
Ann Arbor, Michigan, 48104, United States
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Clinical Research Site
Springfield, Missouri, 65810, United States
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Clinical Research Site
Albuquerque, New Mexico, 87102, United States
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Clinical Research Site
Manlius, New York, 13104, United States
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Clinical Research Site
Williamsville, New York, 14221, United States
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Clinical Research Site
High Point, North Carolina, 27262, United States
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Clinical Research Site
Oklahoma City, Oklahoma, 73106, United States
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Clinical Research Site
Philadelphia, Pennsylvania, 19114, United States
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Clinical Research Site
Charleston, South Carolina, 29406, United States
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Clinical Research Site
Mt. Pleasant, South Carolina, 29464, United States
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Clinical Research Site
Memphis, Tennessee, 38119, United States
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Clinical Research Site
Nashville, Tennessee, 37203, United States
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Clinical Research Site
Austin, Texas, 78731, United States
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Clinical Research Site
Salt Lake City, Utah, 84107, United States
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Clinical Research Site
Charlottesville, Virginia, 22911, United States