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Bacterial infectious disease
MONDO:0005113An acute infectious disorder that is caused by gram positive or gram negative bacteria; representative examples include pneumococcal, streptococcal, salmonella, and meningeal infections.
Also known as: Bacteria caused disease or disorder, Bacteria disease or disorder, Bacteria infectious disease, bacterial disease, bacterial disorder, bacterial infection, bacterial infectious disease, infection, bacterial
2079 clinical trials for this condition and its sub-types, 96 tagged with Bacterial infectious disease itself.
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Sub-types of Bacterial infectious disease
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Primary bacterial infectious disease 0 trials · 593 incl. sub-types
37 sub-types
- Tuberculosis 218 trials · 299 incl. sub-types Sub-types →
- Syphilis 47 trials · 56 incl. sub-types Sub-types →
- Gonorrhea 49 trials Sub-types →
- Tetanus 44 trials Sub-types →
- Lyme disease 31 trials
- Diphtheria 27 trials Sub-types →
- Mycobacterium avium complex disease 22 trials
- Anthrax infection 17 trials · 20 incl. sub-types Sub-types →
- Salmonellosis 5 trials · 19 incl. sub-types Sub-types →
- Cholera 16 trials
- Shigellosis 14 trials
- Leprosy 11 trials · 12 incl. sub-types Sub-types →
- Leptospirosis 9 trials Sub-types →
- Botulism 5 trials Sub-types →
- Listeriosis 4 trials Sub-types →
- Plague 2 trials · 4 incl. sub-types Sub-types →
- Buruli ulcer disease 3 trials
- Q fever 3 trials
- Campylobacteriosis 3 trials Sub-types →
- Melioidosis 3 trials
- Brucellosis 2 trials Sub-types →
- Legionellosis 1 trial · 2 incl. sub-types Sub-types →
- Relapsing fever 2 trials Sub-types →
- Bartonellosis 0 trials · 1 incl. sub-types Sub-types →
- Ehrlichiosis 1 trial Sub-types →
- Granuloma inguinale 0 trials · 1 incl. sub-types Sub-types →
- Ornithosis 1 trial
- Pinta disease 1 trial
- Borrelia miyamotoi disease 0 trials
- Chancroid 0 trials
- Glanders 0 trials
- Rhinoscleroma 0 trials
- Sennetsu fever 0 trials
- Spirillary rat-bite fever 0 trials
- Staphyloenterotoxemia 0 trials
- Streptobacillary rat-bite fever 0 trials
- Tularemia 0 trials Sub-types →
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Mycobacterial infectious disease 23 trials · 361 incl. sub-types
7 sub-types
- Tuberculosis 218 trials · 299 incl. sub-types Sub-types →
- Pulmonary non-tuberculous mycobacterial infection 48 trials
- Mycobacterium avium complex disease 22 trials
- Leprosy 11 trials · 12 incl. sub-types Sub-types →
- Buruli ulcer disease 3 trials
- Mycobacterium xenopi infection 2 trials
- Aquarium granuloma 0 trials
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Gram-negative bacterial infections 33 trials · 301 incl. sub-types
15 sub-types
- Helicobacter pylori infectious disease 115 trials
- Treponema infectious disease 7 trials · 58 incl. sub-types Sub-types →
- Chlamydiaceae infections 1 trial · 55 incl. sub-types Sub-types →
- Bordetellosis 0 trials · 39 incl. sub-types Sub-types →
- Moraxellaceae infectious disease 0 trials · 8 incl. sub-types Sub-types →
- Pneumonia caused by gram negative bacteria 5 trials · 7 incl. sub-types Sub-types →
- Rickettsiaceae infectious disease 0 trials · 4 incl. sub-types Sub-types →
- Burkholderia infectious disease 0 trials · 3 incl. sub-types Sub-types →
- Anaplasmataceae infectious disease 0 trials · 2 incl. sub-types Sub-types →
- Bartonellaceae infectious disease 0 trials · 1 incl. sub-types Sub-types →
- Bacteroidaceae infectious disease 0 trials Sub-types →
- Desulfovibrionaceae infectious disease 0 trials
- Fusobacteriaceae infectious disease 0 trials Sub-types →
- Bacterial meningitis caused by gram-negative bacteria 0 trials Sub-types →
- Streptobacillus infectious disease 0 trials Sub-types →
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Commensal bacterial infectious disease 0 trials · 273 incl. sub-types
6 sub-types
- Toxic shock syndrome 225 trials Sub-types →
- Chlamydia trachomatis infectious disease 37 trials · 48 incl. sub-types Sub-types →
- Lemierre syndrome 0 trials
- Actinomycosis 0 trials Sub-types →
- Gas gangrene 0 trials
- Staphylococcal scalded skin syndrome 0 trials
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Gram-positive bacterial infections 7 trials · 253 incl. sub-types
6 sub-types
- Streptococcal infection 19 trials · 132 incl. sub-types Sub-types →
- Clostridium infectious disease 48 trials · 97 incl. sub-types Sub-types →
- Bacillaceae infectious disease 1 trial · 20 incl. sub-types Sub-types →
- Actinomycetales infectious disease 1 trial Sub-types →
- Erysipelothrix infectious disease 0 trials Sub-types →
- Infection caused by Bifidobacterium 0 trials
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Pulpitis 191 trials
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Bacterial sexually transmitted disease 8 trials · 114 incl. sub-types
5 sub-types
- Treponema infectious disease 7 trials · 58 incl. sub-types Sub-types →
- Chlamydia infectious disease 34 trials · 55 incl. sub-types Sub-types →
- Gonorrhea 49 trials Sub-types →
- Granuloma inguinale 0 trials · 1 incl. sub-types Sub-types →
- Chancroid 0 trials
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Bacterial infectious disease with sepsis 78 trials · 113 incl. sub-types
5 sub-types
- Neonatal sepsis 35 trials
- Lemierre syndrome 0 trials
- Pasteurella hemorrhagic septicemia 0 trials
- Gas gangrene 0 trials
- Meningococcemia 0 trials
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Anaerobic bacteria infectious disease 2 trials · 100 incl. sub-types
10 sub-types
- Clostridium infectious disease 48 trials · 97 incl. sub-types Sub-types →
- Actinomycetales infectious disease 1 trial Sub-types →
- Bacteroides infectious disease 0 trials
- Fusobacterium infectious disease 0 trials
- Peptostreptococcus infectious disease 0 trials
- Anaerobic balanitis 0 trials
- Anaerobic cellulitis 0 trials
- Anaerobic meningitis 0 trials
- Anaerobic pneumonia 0 trials
- Infection caused by Bifidobacterium 0 trials
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Spirochaetales infections 1 trial · 99 incl. sub-types
4 sub-types
- Treponema infectious disease 7 trials · 58 incl. sub-types Sub-types →
- Lyme disease 31 trials
- Leptospirosis 9 trials Sub-types →
- Borrelia infectious disease 6 trials · 7 incl. sub-types Sub-types →
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Bacterial arthritis 24 trials · 94 incl. sub-types
6 sub-types
- Periprosthetic joint infection 76 trials
- Escherichia coli discitis 0 trials
- Gonococcal infection of joint 0 trials Sub-types →
- Salmonella discitis 0 trials
- Staphylococcus discitis 0 trials
- Streptococcus pneumoniae discitis 0 trials
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Staphylococcal infection 41 trials · 84 incl. sub-types
4 sub-types
- Staphylococcus aureus infection 37 trials · 69 incl. sub-types Sub-types →
- Staphylococcal pneumonia 1 trial Sub-types →
- Staphylococcal toxemia 0 trials · 1 incl. sub-types Sub-types →
- Staphyloenterotoxemia 0 trials
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Bacterial urinary tract infection 55 trials · 81 incl. sub-types
8 sub-types
- Pyelonephritis 8 trials · 21 incl. sub-types Sub-types →
- Acute cystitis 7 trials Sub-types →
- Urethritis 5 trials · 6 incl. sub-types Sub-types →
- Gonococcal cystitis 0 trials Sub-types →
- Neonatal urinary tract infectious disease 0 trials
- Renal tuberculosis 0 trials
- Ureter tuberculosis 0 trials
- Urinary bladder tuberculosis 0 trials
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Clostridium difficile colitis 69 trials
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Bacterial pneumonia 28 trials · 65 incl. sub-types
8 sub-types
- Streptococcal pneumonia 16 trials
- Mycoplasma pneumoniae pneumonia 9 trials
- Klebsiella pneumonia 7 trials
- Pneumonia caused by gram negative bacteria 5 trials · 7 incl. sub-types Sub-types →
- Pneumonia caused by pseudomonas aeruginosa infection 3 trials
- Legionnaires' disease 2 trials
- Staphylococcal pneumonia 1 trial Sub-types →
- Anaerobic pneumonia 0 trials
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Skin disease caused by bacterial infection 13 trials · 57 incl. sub-types
17 sub-types
- Cellulitis 29 trials · 31 incl. sub-types Sub-types →
- Hordeolum 1 trial · 7 incl. sub-types Sub-types →
- Impetigo 5 trials Sub-types →
- Cutaneous anthrax 2 trials
- Erysipelas 1 trial
- Pinta disease 1 trial
- Aquarium granuloma 0 trials
- Bacillary angiomatosis 0 trials
- Bacterial exanthem 0 trials
- Bullous impetigo 0 trials
- Cutaneous diphtheria 0 trials
- Cutaneous syphilis 0 trials Sub-types →
- Cutaneous tuberculosis 0 trials Sub-types →
- Gas gangrene 0 trials
- Gonococcal keratitis 0 trials
- Staphylococcal scalded skin syndrome 0 trials
- Sycosis barbae 0 trials
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Meningococcal infection 47 trials · 55 incl. sub-types
2 sub-types
- Meningococcal meningitis 18 trials
- Meningococcemia 0 trials
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Bifidobacteriales infectious disease 0 trials · 44 incl. sub-types
2 sub-types
- Bacterial vaginosis 44 trials
- Infection caused by Bifidobacterium 0 trials
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Bacterial meningitis 12 trials · 37 incl. sub-types
8 sub-types
- Meningococcal meningitis 18 trials
- Meningeal tuberculosis 7 trials
- Haemophilus meningitis 1 trial
- Escherichia coli meningitis 0 trials
- Listeria meningitis 0 trials
- Anaerobic meningitis 0 trials
- Bacterial meningitis caused by gram-negative bacteria 0 trials Sub-types →
- Streptococcal meningitis 0 trials Sub-types →
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Pseudomonas infection 25 trials · 29 incl. sub-types
1 sub-type
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Escherichia coli infection 26 trials
1 sub-type
- Escherichia coli discitis 0 trials
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Vibrio infectious disease 0 trials · 16 incl. sub-types
2 sub-types
- Cholera 16 trials
- Vibrio vulnificus infectious disease 0 trials
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Bacterial endocarditis 15 trials
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Mycoplasmoides infection 7 trials · 15 incl. sub-types
2 sub-types
- Mycoplasma pneumoniae pneumonia 9 trials
- Mycoplasma encephalitis 0 trials
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Haemophilus infectious disease 14 trials
2 sub-types
- Haemophilus meningitis 1 trial
- Chancroid 0 trials
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Necrotizing soft tissue infection 13 trials
2 sub-types
- Necrotizing cellulitis 0 trials
- Necrotizing myositis 0 trials
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Empyema 10 trials · 11 incl. sub-types
2 sub-types
- Subdural empyema 1 trial
- Tuberculous empyema 0 trials
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Chorioamnionitis 10 trials
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Klebsiella infectious disease 5 trials · 9 incl. sub-types
3 sub-types
- Klebsiella pneumonia 7 trials
- Granuloma inguinale 0 trials · 1 incl. sub-types Sub-types →
- Rhinoscleroma 0 trials
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Rickettsiosis 2 trials · 7 incl. sub-types
3 sub-types
- Rickettsiaceae infectious disease 0 trials · 4 incl. sub-types Sub-types →
- Anaplasmataceae infectious disease 0 trials · 2 incl. sub-types Sub-types →
- Tick-borne relapsing fever 0 trials
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Tracheitis 2 trials · 7 incl. sub-types
1 sub-type
- Laryngotracheitis 1 trial · 5 incl. sub-types Sub-types →
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Peritonsillar abscess 4 trials
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Enterococcus infectious disease 1 trial · 4 incl. sub-types
1 sub-type
- Enterococcus faecalis infection 3 trials
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Yersinia infectious disease 0 trials · 4 incl. sub-types
3 sub-types
- Plague 2 trials · 4 incl. sub-types Sub-types →
- Yersinia enterocolitica infectious disease 0 trials
- Yersinia pseudotuberculosis infectious disease 0 trials Sub-types →
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Bacterial conjunctivitis 3 trials
3 sub-types
- Gonococcal conjunctivitis 0 trials Sub-types →
- Inclusion conjunctivitis 0 trials
- Pseudomembranous conjunctivitis 0 trials Sub-types →
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Bacterial hemorrhagic fever 0 trials · 3 incl. sub-types
1 sub-type
- Scrub typhus 3 trials
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Bacterial gastritis 2 trials
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Fournier gangrene 2 trials
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Septic peritonitis 2 trials
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Opportunistic bacterial infectious disease 0 trials · 1 incl. sub-types
2 sub-types
- Nocardiosis 1 trial
- Cepacia syndrome 0 trials
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Actinobacillus infectious disease 0 trials
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1 sub-type
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Pectobacterium carotovorum infection 0 trials
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Proteus infectious disease 0 trials
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Whipple disease 0 trials
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Bacterial myositis 0 trials
1 sub-type
- Pyomyositis 0 trials
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Botryomycosis 0 trials
2 sub-types
- Cutaneous botryomycosis 0 trials
- Visceral botryomycosis 0 trials
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Idiopathic severe pneumococcemia 0 trials
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Noma 0 trials
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Pasteurellosis 0 trials
1 sub-type
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Pneumonic pasteurellosis 0 trials
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Rat-bite fever 0 trials
2 sub-types
- Spirillary rat-bite fever 0 trials
- Streptobacillary rat-bite fever 0 trials
Most studied deeper sub-types
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New antibiotic vabomere tested in kids for first time
Disease control CompletedThis study is testing a single dose of the antibiotic Vabomere in 39 children from birth to under 18 years old who have serious bacterial infections. The goal is to find the right dose and check how safe and tolerable the drug is. All children are hospitalized and receiving other…
Phase 1 • Sponsor: Rempex (a wholly owned subsidiary of Melinta Therapeutics, LLC) • Aim: Disease control
Last updated Aug 19, 2026 00:00 UTC
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Hospital care model aims to treat opioid addiction and serious infections together
Disease control CompletedThis study tests a care model where hospitalized adults with opioid use disorder and a serious infection receive long-acting injectable buprenorphine from their infectious disease doctors, alongside infection treatment. The goal is to keep patients on effective medication for opi…
Sponsor: Yale University • Aim: Disease control
Last updated Jul 16, 2026 00:00 UTC
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Could a single abutment placement save your jawbone?
Disease control CompletedThis study tests whether placing the final abutment once during dental implant surgery, without removing it during healing, reduces bone loss around the implant compared to standard repeated disconnections. Researchers will also measure patient satisfaction and analyze mouth bact…
Sponsor: University of Valencia • Aim: Disease control
Last updated Jul 15, 2026 00:00 UTC
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New antibiotic oritavancin tested in kids for safety and dosing
Disease control CompletedThis study tested a single dose of the antibiotic oritavancin in 41 children under 18 with suspected or confirmed bacterial infections. The goal was to find the right dose and check for safety and side effects. It was an early-stage trial, so it focused on how the drug moves thro…
Phase 1 • Sponsor: Melinta Therapeutics, LLC • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Brain surgery infection fighter: vancomycin powder put to the test
Disease control CompletedThis study tested whether applying vancomycin powder directly to the surgical wound during brain surgery can reduce infections. Over 1,100 adults having neurosurgery were randomly assigned to receive either the topical vancomycin or standard care. The main goal was to see if the …
Phase 3 • Sponsor: Columbia University • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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A simple blood test may spot severe bacterial infections faster in the ER
Diagnosis CompletedResearchers in Basel are testing whether a blood marker called HNL can help emergency doctors quickly tell whether an infection is bacterial or viral. The study will enroll about 516 adults with suspected infection and signs of physiological disturbance. Doctors will measure HNL …
Sponsor: University Hospital, Basel, Switzerland • Aim: Diagnosis
Last updated Sep 12, 2026 00:00 UTC
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Grinding up samples: a better way to spot bone infections?
Diagnosis CompletedThis study tested two ways of preparing tissue samples to find bacteria in bone and joint infections. One method grinds the sample, while the other uses standard techniques. Researchers wanted to see which method is more accurate at diagnosing infections. The study involved 122 p…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Diagnosis
Last updated Jun 27, 2026 09:01 UTC
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New infection score may improve burn care
Diagnosis CompletedThis study tested a new, low-cost tool called the Intensive Care Infection Score (ICIS) to see if it can better detect bacterial infections in burn patients compared to standard blood tests. Researchers studied 97 adults and children hospitalized for burns. The goal was to improv…
Sponsor: Charles University, Czech Republic • Aim: Diagnosis
Last updated Jun 27, 2026 08:08 UTC
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One-Hour brain infection test could save lives
Diagnosis CompletedThis study tested a new rapid diagnostic panel called QIAstat-Dx that can detect 15 different bacteria, viruses, and fungi causing meningitis and encephalitis in just one hour. Researchers compared its accuracy against standard lab tests using 170 stored spinal fluid samples. If …
Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna • Aim: Diagnosis
Last updated Jun 27, 2026 08:05 UTC
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New blood test could spot dangerous infections in feverish kids faster
Diagnosis CompletedThis study looked at whether a combination of 7 biomarkers in the blood can more accurately diagnose severe bacterial infections in children aged 7 days to 36 months with fever. Researchers enrolled 983 children and compared the biomarker panel's performance against standard test…
Sponsor: Hospices Civils de Lyon • Aim: Diagnosis
Last updated Jun 27, 2026 08:05 UTC
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New PET scan technique aims to sniff out hidden infections
Diagnosis CompletedThis early study tested whether a special PET scan using a radioactive form of vitamin B9 (11C-PABA) can help doctors see infections deep inside the body. Researchers scanned 13 healthy people and patients with known or suspected infections. The goal was to see if this method can…
Sponsor: Johns Hopkins University • Aim: Diagnosis
Last updated Jun 27, 2026 08:03 UTC
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Simple new device could speed up blood infection diagnosis in africa
Diagnosis CompletedThis study tested a new, portable blood culture system called BactInsight in hospitals in Benin and Burkina Faso. The system uses a battery-powered device to detect bacteria in blood samples faster than current manual methods. Researchers compared it to standard lab tests in over…
Sponsor: Institute of Tropical Medicine, Belgium • Aim: Diagnosis
Last updated Jun 27, 2026 08:03 UTC
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New biosensors aim to diagnose infections in minutes
Diagnosis CompletedThis study tested two new types of biosensor platforms to detect viruses, bacteria, and parasites in blood and respiratory samples. The goal was to see if these devices could be accurate, fast, and cheap alternatives to standard lab tests. Researchers enrolled 149 adults with or …
Sponsor: University of Bologna • Aim: Diagnosis
Last updated Jun 27, 2026 08:03 UTC
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New AI-Guided blood test could slash unnecessary antibiotic use
Diagnosis CompletedThis study tested a blood test that measures three proteins (ICAM1, CFHR5, and GRN) to help doctors quickly tell whether a fever is caused by bacteria or a virus. Researchers studied 394 adults with high fever and short illness duration. The goal is to improve diagnosis and reduc…
Sponsor: Qilu Hospital of Shandong University • Aim: Diagnosis
Last updated Jun 27, 2026 07:53 UTC
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Could a Spider-Silk bandage slash surgery infections?
Prevention CompletedThis study tested a special dressing coated with a spider-silk-like chemical (DACC) to see if it prevents infections after vascular surgery. Over 700 adults in the UK were randomly assigned to get either the DACC dressing or a standard one. Researchers checked for infections at 3…
Sponsor: Hull University Teaching Hospitals NHS Trust • Aim: Prevention
Last updated Jun 27, 2026 09:00 UTC
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Labour antibiotic may shield newborns from infections
Prevention CompletedThis study tested whether giving mothers a single 2-gram dose of the antibiotic azithromycin during labour could reduce the risk of skin and soft tissue infections in their babies during the first three months of life. Over 2,000 pregnant women in Fiji took part, receiving either…
Phase 3 • Sponsor: Murdoch Childrens Research Institute • Aim: Prevention
Last updated Jun 26, 2026 14:38 UTC
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Probiotic shows promise in easing antibiotic side effects in kids
Symptom relief CompletedThis study tested whether a probiotic called Bifidobacterium breve PRL2020 could reduce stomach issues like diarrhea in 121 children aged 3-12 who were taking amoxicillin antibiotics. The children took the probiotic alongside their antibiotic treatment. The goal was to see if it …
Sponsor: Liaquat University of Medical & Health Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Scientists probe Drug-Induced sunburn reactions
Knowledge-focused CompletedThis study looks at why some medications, like the antifungal voriconazole, can cause extreme sensitivity to sunlight, leading to severe sunburn-like reactions. Researchers will measure gene activity in skin samples from 62 participants, including healthy volunteers and patients …
Phase 1 • Sponsor: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) • Aim: Knowledge-focused
Last updated Sep 03, 2026 00:00 UTC
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Can High-Dose amoxicillin be made safer?
Knowledge-focused CompletedThis study looks at patients receiving high-dose intravenous amoxicillin for serious bacterial infections. Researchers will measure drug levels in the blood during the first week to see how much they vary between patients and within the same patient. They will also check for side…
Phase 4 • Sponsor: University Hospital, Clermont-Ferrand • Aim: Knowledge-focused
Last updated Aug 09, 2026 00:00 UTC
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Can a simple kidney test help beat superbugs in the ICU?
Knowledge-focused CompletedThis study aims to see if using a blood marker called Cystatin C can better predict how antibiotics work in critically ill ICU patients with drug-resistant infections. Researchers will compare Cystatin C to standard kidney function tests and a dye-based gold-standard test. The go…
Phase 4 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Aug 02, 2026 00:00 UTC
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Study links NSAIDs to severe bacterial infections
Knowledge-focused CompletedThis study looked at 335 adults hospitalized with bacterial infections to see if taking NSAIDs (like ibuprofen) before admission made their infections more severe. Researchers compared those with complicated infections (abscesses, needing surgery) to those with simpler infections…
Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
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Pandemic shifts germ landscape: study reveals new patterns in respiratory infections
Knowledge-focused CompletedThis study looked at 537 patients with respiratory infection symptoms to see how the types of viruses and bacteria changed from the COVID-19 pandemic period to after it. Researchers used a special PCR test to detect multiple germs at once. The goal was to understand how pandemic …
Sponsor: Hisar Intercontinental Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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New blood tests could speed up infection detection
Knowledge-focused CompletedThis study looked at 102 patients with bloodstream infections to compare standard lab cultures with two new rapid detection methods. The goal was to see how long germs stay in the blood and whether the new tests can give faster, more accurate results. This information could help …
Sponsor: The University of Queensland • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Yogurt study probes how friendly bacteria survive the gut
Knowledge-focused CompletedThis study looked at whether eating fermented dairy products with three types of Bifidobacterium (with or without prebiotic fibers) for 28 days changes the variety of gut bacteria in healthy people aged 45 to 60. 182 participants ate either a test yogurt or a regular yogurt. The …
Sponsor: Danone Global Research & Innovation Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Scientists seek perfect antibiotic dose for young burn victims
Knowledge-focused CompletedThis study aimed to find the best dose of the antibiotic ceftazidime for critically ill children with severe burns. Researchers took blood samples from 3 children to measure how the drug moves through the body. The goal was to learn how to personalize dosing to improve treatment …
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Hidden bacteria in artery plaques may predict Post-Surgery risks
Knowledge-focused CompletedThis study examined 200 adults who had surgery to remove plaque from their carotid arteries. Researchers identified bacteria living inside the plaques and tracked whether certain types were linked to later strokes, re-narrowing of the artery, or death. The goal was to learn which…
Sponsor: Tang-Du Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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New antibiotic studied in kids: first step toward better infection treatment
Knowledge-focused CompletedThis early-phase study tested a single dose of the antibiotic omadacycline (Nuzyra) in 23 children aged 8 to 17 who were hospitalized with bacterial infections. Researchers measured how the drug moved through the body and checked for side effects. The goal was to gather safety an…
Phase 1 • Sponsor: Paratek Pharmaceuticals Inc • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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New imaging method could spot hidden bacteria
Knowledge-focused CompletedThis study tested a new imaging technique using a radioactive tracer called 11C-trimethoprim to see how it spreads in the bodies of 16 adults with suspected bacterial infections. Participants had PET/CT scans to track the tracer over time. The goal was to learn how the tracer beh…
Phase 1 • Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Liver study tracks antibiotic levels in Fluid-Filled bellies
Knowledge-focused CompletedThis study looked at how the antibiotic ceftriaxone moves through the blood and belly fluid in 20 people with severe liver disease and fluid buildup (ascites). Researchers collected leftover blood and fluid samples to measure drug levels. The goal was to better understand dosing …
Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Healthy volunteers needed to donate stool for gut research
Knowledge-focused CompletedThis study collected stool samples from 110 healthy adults aged 18-60 to help Danone advance its research on digestive health. Participants had to have regular bowel movements and be in good health. No treatment or medication was given; the goal was simply to gather enough usable…
Sponsor: Danone Global Research & Innovation Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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New antibiotic cocktail takes first step in human safety trial
Knowledge-focused CompletedThis early-stage trial tested the safety and drug interactions of an experimental oral antibiotic combination (QPX7831 plus ceftibuten) in 53 healthy adults. The goal was to see how the body processes the drugs and whether they cause side effects. Results will help decide safe do…
Phase 1 • Sponsor: Qpex Biopharma, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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New antibiotic cocktail tested for safety in 60 volunteers
Knowledge-focused CompletedThis completed Phase 1 study tested a combination of two antibiotics, cefiderocol and xeruborbactam, in 60 healthy adults. The goal was to see how the drugs interact in the body and whether they are safe. Participants received either the drug combo or a placebo, and researchers m…
Phase 1 • Sponsor: Qpex Biopharma, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Wearable pump trial aims to free hospital patients from IV stands
Knowledge-focused CompletedThis study tested special wearable pumps (elastomeric pumps) to give antibiotics through a drip to hospital patients. Nine adults with bacterial infections took part to see if the pumps are safe, easy to use, and could save time and money compared to traditional methods. The goal…
Sponsor: Stuart Bond • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC