Study links NSAIDs to severe bacterial infections

NCT ID NCT02794831

Completed Knowledge-focused Sponsor: Nantes University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 335 adults hospitalized with bacterial infections to see if taking NSAIDs (like ibuprofen) before admission made their infections more severe. Researchers compared those with complicated infections (abscesses, needing surgery) to those with simpler infections. The goal was to understand if NSAID use is linked to worse outcomes, such as spread of infection or need for invasive procedures.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: NSAIDs (non-steroidal anti-inflammatory drugs, e.g., ibuprofen)
What this could lead to: If it succeeds, this could clarify whether NSAIDs make bacterial infections more severe, guiding safer use of these common pain relievers.
What could go wrong: This is an observational study, not a treatment trial, so it cannot prove cause and effect. Results may be influenced by other factors like underlying health or delayed care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BACTERIAL INFECTION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

bacterial infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BACTERIAL INFECTION

Contacts and locations

Locations

CHU de Nantes

Nantes, 44093, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.