Hospital care model aims to treat opioid addiction and serious infections together
NCT ID NCT04180020
First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time
Summary
This study tests a care model where hospitalized adults with opioid use disorder and a serious infection receive long-acting injectable buprenorphine from their infectious disease doctors, alongside infection treatment. The goal is to keep patients on effective medication for opioid use disorder after discharge. Participants are randomly assigned to this new model or to standard care, and researchers track whether they stay on treatment at 12 weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- long-acting injectable buprenorphine
- What this could lead to
- If successful, this model could improve treatment retention for people with opioid use disorder and serious infections, reducing relapse and complications.
- What could go wrong
- This is a relatively small study testing a care model, not a new drug. Results may not apply broadly, and the intervention depends on hospital resources and patient willingness.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Penn State Health Milton S. Hershey Medical Center
Hershey, Pennsylvania, 17033, United States
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Prisma Health
Greenville, South Carolina, 29650, United States
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Yale New Haven Hospital
New Haven, Connecticut, 06520, United States
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