New AI-Guided blood test could slash unnecessary antibiotic use

NCT ID NCT07205575

Completed Diagnosis Sponsor: Qilu Hospital of Shandong University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a blood test that measures three proteins (ICAM1, CFHR5, and GRN) to help doctors quickly tell whether a fever is caused by bacteria or a virus. Researchers studied 394 adults with high fever and short illness duration. The goal is to improve diagnosis and reduce unnecessary antibiotic prescriptions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Proteomic Biomarker Panel (blood test measuring ICAM1, CFHR5, and GRN proteins)
What this could lead to: If successful, this blood test could help doctors quickly tell whether a fever is caused by bacteria or a virus, reducing unnecessary antibiotic use.
What could go wrong: This is a completed diagnostic study, not a treatment trial. The test's accuracy may not be high enough for routine use, and results may not apply to all patient groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

bacterial infectious disease infectious disease with sepsis Sepsis viral infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE FEBRILE ILLNESS BACTERIAL INFECTIONS SEPSIS VIRAL INFECTIONS

Contacts and locations

Locations

Qilu Hospital of Shandong University

Jinan, Shandong, 250012, China

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