Qilu Hospital Of Shandong University

This phase 2 trial tests a combination of three drugs (tislelizumab, anlotinib, and nab-paclitaxel) given before surgery to people with stage III non-small cell lung cancer. The goal is to see if this approach can eliminate or greatly reduce the tumor before it is removed. The st…

This study tests whether using special brain monitors (near-infrared light, ultrasound, and brain wave tracking) can help doctors better manage oxygen levels in the brain for people on life support after a cardiac arrest. The goal is to see if this approach increases the number o…

This study compares three approaches for people with both gallstones and bile duct stones: a gallbladder-preserving procedure using an endoscope, ERCP plus gallbladder removal surgery, or conservative management with medication or watchful waiting. Researchers will track complica…

This study tests whether spironolactone, a common diuretic, can improve learning and behavior in children aged 3–10 with NCOR gene mutations, which are linked to autism spectrum disorder. Only 2 children will be enrolled, and researchers will measure changes in intelligence and a…

This study tests whether placing a small plastic tube (stent) in the pancreas during a gallstone removal procedure can prevent pancreatitis, a painful inflammation. 88 adults with both gallbladder and common bile duct stones will be randomly assigned to receive either standard ca…

This phase 2 trial is testing whether a combination of two immunotherapy drugs (iparomlimab and tuvonralimab, together called QL1706) plus standard chemotherapy can help people with advanced HER2-negative stomach cancer that has low PD-L1 levels. The study will enroll 77 particip…

This study tests whether a 3-day low-leucine diet can make chemotherapy and immunotherapy work better for people with advanced stomach cancer. Researchers believe the diet may activate immune cells in the tumor. The trial involves 73 participants and will measure tumor shrinkage …

This study tests whether a short-term diet low in leucine (an amino acid) can make standard chemo-immunotherapy work better for stomach cancer patients. About 108 people will follow the diet for 3 days during each treatment cycle. Researchers will check if this approach improves …

This study tests whether growing a patient's tumor cells in the lab (organoids) can help doctors choose the most effective chemotherapy after bladder cancer surgery. Researchers will compare survival rates of patients whose chemo was guided by organoid tests versus standard care.…

This study uses lab-grown mini-tumors (organoids) from bladder cancer patients to see which anti-HER-2 drug works best. It compares survival rates of patients whose treatment is guided by these organoids versus standard protein testing. The goal is to improve one-, two-, and thre…

This study tests whether eating quinoa-based foods instead of regular starches can improve blood sugar and fat levels in people with early-stage type 2 diabetes. Sixty adults with diabetes for less than 5 years will eat quinoa noodles, powder, or cookies for 14 weeks. Researchers…

This study tests whether injecting two drugs directly into the belly can help control fluid buildup (ascites) caused by stomach cancer. The drugs are sintilimab, which helps the immune system fight cancer, and zoledronic acid, which may slow cancer growth. The trial involves 24 a…

This study looks at 2,600 heart attack patients who had a stent placed and also have an H. pylori infection. Half will get a 2-week course of vonoprazan plus amoxicillin to treat the infection, while the other half gets a standard 6-month acid blocker (pantoprazole). The goal is …

This study tests a combination of hormone therapy, chemotherapy, and targeted ultrasound for men with metastatic prostate cancer that has spread widely. The goal is to see if adding focused ultrasound to standard triple therapy can better control the disease. About 116 men will t…

This study tests whether a magnetocardiography (MCG) device can detect reduced blood flow to the heart muscle in people with acute chest pain but no major artery blockages. About 3,786 participants will undergo MCG scanning, and results will be compared to a standard ultrasound t…

This study is testing a computer program called iEUS-SPL that helps doctors identify different types of solid growths in the pancreas during an endoscopic ultrasound. About 383 adults with suspected pancreatic lumps will take part. The goal is to see if the AI can correctly tell …

This study tests an artificial intelligence system designed to automatically score precancerous changes in the stomach lining during endoscopy. Researchers will compare the AI's scores to those of expert doctors in 3,000 participants aged 40-75. The goal is to see if the AI can r…

This study tests a new, noninvasive device that uses ultra-sensitive magnetocardiography to detect heart attacks. Researchers will enroll nearly 4,000 healthy volunteers and chest pain patients to see if this magnetic scan can identify heart damage more accurately than current me…

This study aims to see if a new device called magnetocardiography (MCG) can quickly and accurately detect blocked arteries in people with suspected heart attack symptoms. Researchers will compare MCG results with standard tests in about 14,000 adults. If successful, MCG could hel…

This study tests whether inhaling an antibiotic called colistin can prevent ventilator-associated pneumonia (VAP) in ICU patients at high risk for drug-resistant infections. About 508 adults on breathing machines for at least two days will receive either colistin or a placebo via…

This study looks at two different ways to reconnect the stomach after surgery for upper stomach cancer. The goal is to see which method causes less acid reflux and helps patients feel better and eat better. About 52 adults with early-stage stomach cancer will take part across six…

This study tests whether a non-invasive brain stimulation technique called high-frequency rTMS can improve cognitive problems that often follow a stroke. Researchers will use brain imaging to see how the treatment affects brain activity. The trial aims to enroll 40 adults aged 35…

This study tests whether traditional Chinese acupuncture can help people whose stomachs stop working properly after partial stomach removal surgery. 176 adults will receive either real or sham acupuncture alongside standard care. The goal is to see if acupuncture shortens the tim…

This study tests whether virtual reality (VR) training in a simulated home environment can improve arm and hand function in people recovering from a stroke. Researchers will compare VR-based task-oriented training to standard therapy in 86 participants. They will also use brain s…

This study tests if a long-acting painkiller (liposomal bupivacaine) works better than a standard one (ropivacaine) for pain after upper abdominal surgery. About 146 adults having open surgery will receive one of the two drugs injected into the belly lining before the incision is…

This study tests whether watching real-life swallowing movements (like a family member eating) can improve swallowing function in stroke patients with dysphagia. Ninety participants will be split into three groups: standard therapy, therapy plus watching swallowing videos, or the…

This study looks at proteins and metabolites in the body fluids of 60 people with narcolepsy, a rare sleep disorder. The goal is to find biological markers that could explain what causes the condition and help doctors diagnose it more accurately. Participants provide samples for …

This study is testing a new way to choose chemotherapy for muscle-invasive bladder cancer. Doctors will grow a miniature version of a patient's tumor in the lab (called an organoid) and test different drugs on it to see which works best. Then, the patient receives the drug that k…

This study looks at DNA methylation patterns in 100 people with severe liver failure caused by hepatitis B. Researchers aim to build a model that predicts how the disease will progress, which could help doctors make better treatment decisions. The study is observational and does …

This study tests a new method to help choose cancer drugs for people with hard-to-treat solid tumors. Doctors take a small piece of the tumor, grow it in the lab, and test many drugs on it to see which works best. Then they give that drug to the patient. The goal is to see if thi…

This study looks at whether doing an endoscopic ultrasound (EUS) at the same time as a standard bile duct procedure (ERCP) helps doctors make better treatment choices. 214 adults with pancreatic or bile duct diseases will be randomly assigned to get either the combined procedure …