Qilu Hospital Of Shandong University

This trial tests whether starting a temporary balloon pump in the aorta before the standard artery-opening procedure (angioplasty) can improve outcomes for people who arrive at the hospital 4 to 12 hours after a major heart attack. Half of the participants will receive the balloo…

This trial tests an artificial intelligence system called ADTPS that helps doctors remove early-stage esophageal cancer or precancerous lesions using a scope. The AI analyzes live images during the procedure and overlays a suggested cutting path on the screen. Half of the partici…

This trial compares a 14-day course of vonoprazan plus minocycline against two other dual therapies (vonoprazan with amoxicillin or tetracycline) for eradicating Helicobacter pylori, a common stomach infection linked to ulcers and cancer. About 492 adults who have never been trea…

This trial compares two ways to eradicate H. pylori, a common stomach infection linked to ulcers and stomach cancer. One group receives a 10-day course of a high-dose acid blocker plus one antibiotic, while the other gets the standard 14-day four-drug regimen. The goal is to see …

This trial tests a new method called Longitude-Latitude-Depth (LLD) localization, which uses 3D mapping from a CT scan to guide surgeons to small lung nodules without a needle puncture. It is being compared to the standard CT-guided needle localization in adults with single perip…

This study looks at how well a combination of two drugs, iparomlimab and tuvonralimab (called QL1706), works for people with recurrent or metastatic cervical cancer that has worsened after platinum-based chemotherapy. Researchers will compare outcomes of those receiving QL1706 to…

This study tests whether adding a 5-day fasting-mimicking diet (low-calorie, low-protein) to the usual combination of toripalimab (an immunotherapy) and axitinib (a targeted drug) can help people with advanced kidney cancer. The trial will enroll 43 adults who have not had prior …

This study looks at a new, less invasive way to treat aneurysms in the arteries that supply the stomach, liver, and spleen. Instead of traditional surgery or X-ray-guided procedures, doctors will use an endoscope with ultrasound to guide tiny coils and glue directly into the aneu…

This study tests whether dapagliflozin, a drug already used for diabetes, can improve heart function in people hospitalized with acute heart failure. About 188 participants will take the drug or not for three months, and doctors will use special ultrasound imaging to measure chan…

This study tests whether inserting a heart pump (IABP) early, before severe shock develops, can reduce deaths in patients who develop a hole in the heart after a heart attack. The trial will enroll 100 patients across 5 centers, randomly assigning half to receive the pump within …

This study tests whether using stool biomarkers (fecal calprotectin and fecal immunochemical test) to guide treatment adjustments can prevent relapses in people with ulcerative colitis. About 240 adults in remission will be randomly assigned to either biomarker-guided therapy or …

This study tests a new procedure using an endoscopic ultrasound to guide the injection of tiny particles into the spleen, reducing blood flow and lowering the risk of dangerous bleeding in people with liver cirrhosis. The goal is to see if this method is safer and more effective …

This early study tests a new treatment called Plasma-Activated Saline Solution (PASS) for bladder cancer. Five patients will receive a one-week course of PASS infused directly into the bladder before their scheduled surgery. Researchers will check if the treatment shrinks tumors …

This study tests whether two drugs, Vedisertib and Toripalimab, can shrink muscle-invasive bladder cancer so patients can keep their bladder. About 59 adults with early-stage cancer will receive the drugs in cycles, with regular checks to see if the cancer disappears. If it does,…

This study tests whether a special cardiac rehabilitation program can improve muscle strength and reduce inflammation in elderly patients with both heart disease and sarcopenia (age-related muscle loss). One hundred participants will either receive rehab plus standard care or sta…

This phase 2 trial tests a combination of three drugs—disitamab vedotin, iparomlimab, and tuvonralimab—in 33 women with HER2-expressing recurrent cervical cancer that has progressed after first-line treatment. The goal is to see if the combo can shrink tumors or slow the disease.…

This study tests whether a combination of two immunotherapy drugs (iparomlimab and tuvonralimab) plus chemotherapy can shrink tumors before surgery in people with stage III colon cancer that is microsatellite stable (pMMR/MSS). About 21 participants will receive four cycles of th…

This study tests whether combining two stool tests—fecal immunochemical test (FIT) and fecal calprotectin (FC)—can accurately detect precancerous or cancerous changes in people with long-standing ulcerative colitis. Participants will provide stool samples and then undergo a speci…

This study looks at whether using a special heart scan (coronary CTA plus CT-FFR) helps doctors make better decisions for people with chest pain who are at moderate risk. About 2,000 emergency room patients will be randomly assigned to get this scan or standard care. The goal is …

This study aims to see if a simple breath test can help doctors quickly tell which patients with chest pain are at high risk for a heart attack or other serious condition. Researchers will collect breath samples from 6,000 adults coming to the emergency room with chest pain and a…

This study tests whether an artificial intelligence (AI) system can help doctors more accurately score a stomach condition called gastric intestinal metaplasia, which can lead to cancer. Eight endoscopists will review videos of stomach exams, some with AI help and some without, t…

This study tests whether a small, wearable patch that stimulates a nerve in the leg can help men who still have bladder symptoms after prostate surgery. Participants will either receive behavioral therapy alone or behavioral therapy plus the patch for 12 weeks. The goal is to see…

This study will test whether a wearable device that stimulates a nerve in the leg can help women with overactive bladder and frequent nighttime urination. Participants will either use the device plus behavioral therapy or behavioral therapy alone. The goal is to see if the device…

This study looks at whether taking a daily probiotic powder can help adults with overactive bladder (OAB) and anxiety. About 218 people will take either probiotics or a placebo for 12 weeks, while everyone also learns bladder training. The main goals are to see if probiotics redu…

This study tests whether stimulating nerves on both sides of the lower spine works better than just one side for people with neurogenic bladder—a condition where nerve damage causes bladder control problems. Twenty-nine adults with incomplete spinal nerve injuries will be randoml…

This study tests whether a real-time artificial intelligence system can help doctors find and stop bleeding faster during a minimally invasive surgery called endoscopic submucosal dissection (ESD), used to remove early-stage digestive tract cancers. About 160 patients will be ran…

This study will test a new, non-invasive treatment called transcranial photobiomodulation (tPBM) for children with ADHD. The treatment uses light to stimulate the brain. Researchers will enroll 54 children aged 6 to 18 to see if tPBM can improve ADHD symptoms, sleep, and brain ac…

This trial investigates whether an online booster training system helps medical students retain high-quality CPR skills months after their initial course. Participants are medical students who have completed a standard CPR class and are randomly assigned to either receive monthly…

This study will collect blood from 3 children with Williams syndrome and 3 healthy children. Scientists will turn blood cells into stem cells and then into brain cells to study how the brain develops differently in Williams syndrome. The goal is to understand the disease better, …

This study looks at how the brains of children with Williams syndrome and autism differ, focusing on social and thinking skills. Researchers will compare 75 children aged 3-12 from three groups: those with Williams syndrome, those with autism, and typically developing kids. No tr…

This study looks at how different altitudes change the way people perceive time. Researchers will use a special chamber to simulate altitudes from 500 to 3000 meters. 46 healthy adults will complete timing tasks while their heart rate and oxygen levels are monitored. The goal is …

This study will compare the costs of two types of sacral neuromodulation devices—rechargeable and non-rechargeable—for treating neurogenic lower urinary tract dysfunction. Researchers will track expenses in 268 patients who have not responded to standard treatments. The goal is t…