New 3D lung mapping could replace needle punctures for small nodule surgery

NCT ID NCT07675889

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This trial tests a new method called Longitude-Latitude-Depth (LLD) localization, which uses 3D mapping from a CT scan to guide surgeons to small lung nodules without a needle puncture. It is being compared to the standard CT-guided needle localization in adults with single peripheral lung nodules 0.8-2 cm in size who are undergoing video-assisted surgery. The goal is to see if LLD is as accurate but causes fewer complications and speeds recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Longitude-Latitude-Depth (LLD) localization procedure
What this could lead to
If successful, this could offer a safer, less invasive way to locate small lung nodules during surgery, reducing pain and recovery time.
What could go wrong
This is a non-inferiority trial, so the new method may prove no better than the standard CT-guided approach. Results may not apply to larger or deeper nodules.

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Conditions

The condition(s) this trial relates to.

Multiple Pulmonary Nodules pulmonary coin lesion

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Linqing People's Hospital

    Linqing, Shandong, 252600, China

  • Ningxia Hui Autonomous Region People's Hospital

    Yinchuan, Ningxia, 750021, China

  • Qilu Hospital of Shandong University

    Jinan, Shandong, 250012, China

  • Xingyi People's Hospital

    Xingyi, Guizhou, 562400, China

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