Two-Week stool test may forecast ulcerative colitis Flare-Ups a year in advance
NCT ID NCT07111273
First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time
Summary
This study is testing whether changes in two stool markers — a fecal immunochemical test (qFIT) and calprotectin (FC) — measured two weeks after starting standard therapy can predict whether people with ulcerative colitis will relapse or need stronger medication within a year. Researchers will follow 100 adults with active UC who have never taken biologic drugs, collecting stool samples at weeks 0, 2, and 4. The goal is to see if a drop of more than 50% or a return to normal levels in both markers can serve as an early warning sign, helping doctors tailor treatment sooner.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- fecal immunochemical test (qFIT) and fecal calprotectin (FC) measurement
- What this could lead to
- If early stool marker changes reliably predict relapse, doctors could adjust treatment sooner, potentially preventing flare-ups and reducing the need for stronger drugs.
- What could go wrong
- This is an observational study, not a treatment trial, so it won't directly improve outcomes. The predictive accuracy may be modest, and results may not apply to all UC patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Shandong University
RECRUITINGJinan, Shandong, 250000, China
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