New antibiotic cocktail tested for safety in 60 volunteers
NCT ID NCT06547554
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed Phase 1 study tested a combination of two antibiotics, cefiderocol and xeruborbactam, in 60 healthy adults. The goal was to see how the drugs interact in the body and whether they are safe. Participants received either the drug combo or a placebo, and researchers monitored side effects and drug levels in blood and urine.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
cefiderocol and xeruborbactam (antibiotic combination)
What this could lead to
If successful, this could help develop a new antibiotic combination for hard-to-treat bacterial infections.
What could go wrong
This is a very early Phase 1 study in healthy people, not patients. It only checks safety and how the drugs interact, not whether they work against infections.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Minneapolis Clinic
Minneapolis, Minnesota, 55114, United States