New antibiotic cocktail tested for safety in 60 volunteers
NCT ID NCT06547554
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed Phase 1 study tested a combination of two antibiotics, cefiderocol and xeruborbactam, in 60 healthy adults. The goal was to see how the drugs interact in the body and whether they are safe. Participants received either the drug combo or a placebo, and researchers monitored side effects and drug levels in blood and urine.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- cefiderocol and xeruborbactam (antibiotic combination)
- What this could lead to
- If successful, this could help develop a new antibiotic combination for hard-to-treat bacterial infections.
- What could go wrong
- This is a very early Phase 1 study in healthy people, not patients. It only checks safety and how the drugs interact, not whether they work against infections.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Minneapolis Clinic
Minneapolis, Minnesota, 55114, United States
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