New antibiotic vabomere tested in kids for first time

NCT ID NCT02687906

Ongoing Disease control Sponsor: Rempex (a wholly owned subsidiary of Melinta Therapeutics, LLC) Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a single dose of the antibiotic Vabomere in 39 children from birth to under 18 years old who have serious bacterial infections. The goal is to find the right dose and check how safe and tolerable the drug is. All children are hospitalized and receiving other antibiotics during the study.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Vabomere (meropenem-vaborbactam)
What this could lead to: If successful, this could help determine safe and effective dosing of Vabomere for children with serious bacterial infections.
What could go wrong: This is a small, early-phase study with only 39 children, so results may not apply to all kids. Side effects are possible, and the drug may not work better than existing antibiotics.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BACTERIAL INFECTIONS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

bacterial infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BACTERIAL INFECTIONS

Contacts and locations

Locations

Ann & Robert H. Lurie Children's Hospital of Chicago

Chicago, Illinois, 60614, United States
Arkansas Children's Hospital

Little Rock, Arkansas, 72202, United States
Children's Hospital of Orange County

Orange, California, 92868, United States
Rady Children's Hospital San Diego

San Diego, California, 92123, United States
Rainbow Babies and Childrens Hospital

Cleveland, Ohio, 44106, United States
Ronald Reagan UCLA Medical Center

Los Angeles, California, 90095, United States
Rutger's University

New Brunswick, New Jersey, 08901, United States
Toledo Children's Hospital

Toledo, Ohio, 43606, United States
University of Nebraska Medical Center

Omaha, Nebraska, 68114, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.