Centre Hospitalier Universitaire De Nice

This study looked at whether using connected fitness devices (like activity trackers) can help people with spondyloarthritis become more physically active and better manage their condition. 108 adults with stable spondyloarthritis participated. The goal was to see if the devices …

This study tested a new material called Mucoderm, made from donated tissue, to treat receding gums. It was compared to the standard method of using a piece of the patient's own gum tissue. The goal was to see if Mucoderm could cover the exposed tooth roots just as well but with l…

This study tested a procedure to place a small metal tube (stent) in the main vein of the liver to relieve serious symptoms like fluid buildup or bleeding caused by cancer blocking the vein. Researchers looked at 63 patients who had this treatment over 20 years. They checked how …

This study tested whether adding the cholesterol-lowering drug atorvastatin to standard UVB light therapy works better than UVB alone for active vitiligo. 28 adults with active non-segmental vitiligo took part. The goal was to see if the combination could reduce the amount of whi…

This study tested whether adding the drug apremilast to standard UVB light therapy helps restore skin color in people with vitiligo, a condition that causes white patches. Eighty adults with moderate to severe vitiligo received UVB light twice a week for 24 weeks, plus either apr…

This study tested a new drug called avdoralimab, given with strong steroid cream, for bullous pemphigoid—a painful blistering skin condition common in people over 70. Fifteen participants received the combination to see if it helped clear blisters and itching faster than steroids…

This study tested whether a daily probiotic (Lactobacillus rhamnosus Lcr35) can reduce the number of painful canker sores in people who get them often. Twenty adults with recurrent mouth ulcers took either the probiotic or a placebo for 3 months, then were monitored for another 3…

This study looked at whether a simple blood test that finds stray cancer cells (circulating tumor cells) can help detect lung cancer earlier in people at very high risk—smokers over 55 with COPD. About 600 participants had both the blood test and a low-dose CT scan once a year fo…

This study compared two imaging methods for diagnosing female infertility: an MRI with a special dye and a standard X-ray. The goal was to see if the MRI could provide a complete, radiation-free picture of the reproductive organs. Forty women participated, and the researchers mea…

This study tested whether a special ultrasound with contrast dye can be as good as CT scans for checking aortic stents after abdominal aortic aneurysm repair. 40 adults who had a stent placed were scanned with both methods. The goal was to see if ultrasound could detect leaks and…

This study looked at whether a blood test measuring two proteins (sFlt-1 and PlGF) can help doctors decide if a pregnant woman with suspected pre-eclampsia needs to be hospitalized. Pre-eclampsia is a serious condition that can harm both mother and baby, but current tests are not…

This study looked at whether a hormone called glicentin, found in the gut, could help diagnose intestinal ischemia—a condition where blood flow to the intestine is blocked. Researchers measured glicentin levels in 54 people with abdominal pain, including those with confirmed isch…

This study tested a new bioimpedance device (Biody XpertZM3) that measures muscle mass while seated, without sticky electrodes. It compared results to standard DXA scans in 72 older adults. The goal was to see if the simpler device could accurately diagnose sarcopenia, a conditio…

This study looked at whether a blood test (liquid biopsy) can detect a specific genetic change (ALK rearrangement) in lung cancer cells circulating in the blood. The goal is to see if this non-invasive method works as well as a traditional tissue biopsy to guide treatment decisio…

This study tested a minimally invasive procedure called CT-guided trans-facet screw fixation to treat spinal instability that can happen after back surgery. In 24 patients, doctors used CT scans to guide small screws into the spine under local anesthesia, aiming to reduce pain an…

This study tested whether adding a special antioxidant pill (GLISODIN) to standard UVB light therapy helps treat vitiligo better than light therapy alone. Fifty adults with non-segmental vitiligo covering more than 5% of their body took part. The main goal was to see if the combi…

This study tested two similar pain medicines, esketamine and ketamine, in 74 adults with severe pain in the emergency room. The goal was to see which one causes fewer disturbing side effects like dizziness or hallucinations while still relieving pain quickly. Both drugs are given…

This study tested a gentler type of keyhole surgery for removing the appendix, called low impact laparoscopy (LIL). It uses smaller incisions and lower gas pressure in the belly compared to standard laparoscopy. The goal was to see if this method reduces pain after surgery and he…

This study tested whether a specific nerve block (called Quadratus Lumborum Block type 3) can reduce pain and the need for strong painkillers after total hip replacement. 60 adults having planned hip surgery received either the nerve block or a placebo. The main goal was to see i…

This study tested whether adding propofol to ketamine reduces agitation during recovery from sedation in adults with fractures or dislocations. 150 participants were randomly assigned to receive either the drug combination or ketamine alone. The main goal was to see if the combin…

This study tested whether using virtual reality (VR) during medical procedures could help elderly patients feel less pain and anxiety. 87 people over age 60 took part. Researchers compared standard care to care with VR headsets or tablets showing relaxing scenes. The goal was to …

This study looked at whether a special breathing maneuver during weight-loss surgery helps patients recover better. 230 obese adults having bariatric surgery were randomly assigned to receive the maneuver or not. The goal was to see if it reduced shortness of breath and the need …

This study tested a new cream for melasma, a skin condition causing dark patches on the face. The new cream replaces a harsh ingredient (hydroquinone) with a gentler one (thiamidol). 40 adults with melasma were treated and monitored for skin improvement and quality of life. The g…

This study tested a new way to treat chronic pain that doesn't respond to medication. It involved implanting electrodes in two brain areas: one that processes the emotional side of pain and one that handles the physical sensation. The goal was to see if this combined approach was…

This study tested whether using a low-power laser on acupuncture points could help prevent nausea and vomiting caused by chemotherapy in children aged 2 to 20 with cancer. The goal was to see if adding this laser treatment to standard anti-nausea medicine would reduce or eliminat…

This study tested a computer-controlled method (TCI) for giving propofol sedation to 45 adults in the emergency department. The goal was to find the right brain concentration for safe, deep sedation during painful procedures like fixing a broken bone or putting a dislocated joint…

This study looked at whether a type of eye scan called OCT-angiography can help predict how well vision will recover after surgery to remove a pituitary tumor. Researchers measured vision and eye structure in 21 patients before and after surgery. The goal was to see if the scan c…

This study investigated if the Epstein-Barr virus (EBV) is linked to peri-implantitis, a serious infection around dental implants that can lead to implant loss. Researchers measured EBV levels in 30 adults with infected implants and compared them to those with healthy implants. T…

This study looked at whether measuring lactate (a substance in the blood) during CPR can help predict if a person's heart will start beating again after a cardiac arrest outside the hospital. Researchers measured lactate in 77 adults when emergency teams arrived. The goal was to …

This study looked at whether giving iodine supplements to pregnant women with normal thyroid function helps their children's brain development at age 2. Researchers tested 85 children using the Bayley scale. The goal was to see if early iodine can improve thinking and learning sk…

This study looked at 479 adults aged 40 to 75 with knee or hip arthritis to see if having arthritis in the finger joints is linked to more severe arthritis in the lower limbs. Researchers used X-rays and clinical exams to measure joint damage. The goal was to better understand ho…

This study looked at 659 patients who had surgery to fix a bulge in the main belly artery (abdominal aortic aneurysm). Doctors compared two ways to check for problems after surgery: a CT scan (which uses X-rays) and an ultrasound (which uses sound waves). The goal was to see if u…

This study looked at how teenagers with autism or schizophrenia understand emotions, intentions, and social situations compared to healthy teens. Researchers measured brain activity while participants performed tasks like recognizing facial expressions. The goal was to find out i…

This study looked at 52 adults with membranous nephropathy, an autoimmune kidney disease. Researchers tested a new blood test that measures specific antibodies to see if it could predict which patients would get worse and need dialysis. The goal was to confirm earlier findings th…

This study looked at how mental and muscle fatigue change the ability of older adults to walk while doing a counting task. 66 participants, both younger (20-40) and older (65-90), completed walking and counting tests before and after fatigue tasks. The goal was to understand how …

This study looked at how well the thyroid works in pregnant women who took iodine supplements compared to those who did not. Researchers tracked 111 women throughout their pregnancies to set normal thyroid values for each trimester. The goal was to find better ways to spot iodine…

This study tested how accurately a robot system called Neurolocate can guide deep brain stimulation surgery. 18 patients with Parkinson's disease, dystonia, or tremor took part. The goal was to see if the robot hits its target as planned, which could make surgery faster and more …

This study looks at how sleep is disturbed in people with Alzheimer's disease. Researchers want to learn how changes in daily sleep-wake cycles affect daytime alertness. The study involves 70 participants, including those with memory problems and healthy volunteers. They will kee…

This study looked at whether a special kidney scan (scintigraphy) can find early kidney damage in children and young adults with sickle cell disease. Standard tests often miss these problems until they are advanced. The goal was to improve annual check-ups so that kidney issues c…

This study tested whether a mobile app (myFSHD) can help doctors remotely monitor people with Facioscapulohumeral muscular dystrophy (FSHD). Seventy adults with FSHD used the app for 12 months to report symptoms and record videos of exercises. The goal was to see if remote monito…

This study investigated if the Epstein-Barr virus (EBV) contributes to inflammation in oral lichen planus, a chronic mouth condition. Researchers measured EBV levels in 13 adults with painful, erosive forms of the disease. The goal was to better understand what causes the conditi…

This study looked at special immune proteins called semaphorins in people with fatty liver disease and NASH. Researchers wanted to see if these proteins are linked to liver damage and inflammation. The study involved 148 obese adults who had liver biopsies and blood tests. The go…

This study looked at 100 people with age-related macular degeneration to measure certain proteins in their eye fluid. The goal was to understand why about 37% of patients do not respond well to standard anti-VEGF injections. Researchers hope this knowledge will help predict treat…

This pilot study looked at how the brain controls fine hand movements and speech in 20 healthy right-handed adults aged 18-35. Using functional MRI, researchers compared brain activity during a manual task and silent speech. The goal was to find shared brain networks, which could…

This study looked at 56 patients in a French hospital who had infections from a rare type of Klebsiella pneumoniae bacteria that can be treated with the common antibiotic amoxicillin. Researchers analyzed the bacteria's DNA to understand why some strains are sensitive to amoxicil…

This study looked at whether exposure to certain chemicals (endocrine disruptors) during pregnancy increases the risk of cryptorchidism (undescended testicles) in baby boys. Researchers compared 95 affected boys with 188 healthy boys, measuring chemical levels in cord blood and b…

This study surveyed over 800 hospital staff and medical students after the 2016 Nice truck attack to understand how such traumatic events affect mental health. Researchers aimed to document the psychological impact and improve support systems for future emergencies. Participants …

This study looked at nearly 1,000 older adults (65 and older) who could walk without help. Researchers used walking tests, strength measurements, and questionnaires to understand frailty and how physical activity might help. The goal was to find ways to keep seniors independent l…

This study looked at 22 people with advanced (stage IV) melanoma to see if DNA from tumors floating in the blood could help doctors understand how the cancer changes during chemotherapy. Researchers compared genetic mutations found in blood samples taken before and after treatmen…

This study looked at skin samples from 170 people with psoriasis, atopic dermatitis (eczema), or healthy skin to understand how a protein called Lyn is involved in inflammation. Researchers measured Lyn activity and related enzymes in both affected and unaffected skin. The goal w…

This study looked at 30 people with cystinosis, a rare disease that causes crystals to build up in the body. Researchers wanted to understand why some patients have lighter skin patches. They studied the genes and skin of participants to find the link between cystinosis and skin …

This study looked at 25 patients treated with radiation for head and neck cancers to see how the treatment changes viruses in the mouth, especially the Epstein-Barr virus (EBV). The goal was to understand why many patients develop severe gum disease after radiation. Researchers a…

This study followed 29 infants who had bronchiolitis (a serious chest infection) in their first year to see if it leads to asthma by age 3. Researchers tested their lung function and did allergy skin tests at several checkpoints. Many children dropped out, but among those who sta…

This study looked at 86 people with rheumatoid arthritis, ankylosing spondylitis, or psoriatic arthritis to see if air pollution triggers flare-ups. Participants reported their symptoms weekly for 6 months, while researchers measured their exposure to pollutants based on where th…

This study looked at 93 patients who had a stem cell transplant for blood cancer. Researchers wanted to see if chronic mouth problems (oral graft-versus-host disease) could be a simple sign that the new immune system is also attacking the cancer. They followed patients over time …

This study looked at 30 people with a type of muscular dystrophy (FSHD1) to measure levels of inflammatory markers in their blood. Researchers compared these levels to healthy controls to see if inflammation plays a role in muscle damage. The goal was to better understand the dis…

This study looked at whether a simple blood test could predict which kidney transplant patients with mild-to-moderate COVID-19 would get worse. Researchers measured a protein called IL-6 in blood samples after stimulation. The goal was to find early warning signs to guide treatme…

This study involved 45 adults who received a kidney transplant. Researchers wanted to learn more about how the drug Advagraf (a type of tacrolimus) works in the body right after transplant and a few months later. The goal was to find better ways to give the right dose of this med…

This study looked at whether blue light from computer or TV screens can darken melasma, a common skin condition causing dark patches on the face. Twelve women with melasma had one side of their face exposed to blue light for 5 days, while the other side was not exposed. Researche…

This study tested a blood test (ELISpot) to detect early immune responses to COVID-19. Researchers aimed to understand infection timing and predict disease severity. About 950 adults participated, including those with confirmed or suspected COVID-19, exposed contacts, and healthy…

This study looked back at 420 patients who had jaw surgery after using either clear aligners or traditional metal braces to straighten their teeth. The goal was to see if one method made surgery easier or led to better early results. The findings help doctors choose the best prep…

This study looked at gene activity in the lining of the nose and lungs of 44 adults, some with allergies and some healthy. The goal was to understand how these tissues differ and how they contribute to allergic diseases like rhinitis and asthma. No treatment was given; it was pur…

This study looked at how a natural cell cleanup process called autophagy might be linked to bone loss in older women. Researchers compared bone samples from women with osteoporosis (some with Alzheimer's disease) to healthy controls. The goal was to understand if poor autophagy c…

This study looked at how people with Alzheimer's disease search for objects in realistic scenes and real-life settings. Researchers tracked eye movements to understand which parts of attention and memory are impaired. The goal was to link these visual difficulties to problems wit…

This study looked at blood samples from 20 adults with relapsed membranous nephropathy, a kidney condition. Researchers tested different immune-modulating drugs in the lab to see how they affect the balance of certain immune cells (Th17 and Treg). The goal was to gather informati…