Lactate levels during CPR may predict heart recovery
NCT ID NCT03325452
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at whether measuring venous lactate (a waste product in the blood) during CPR can help predict if a person's heart will start beating again after a cardiac arrest outside the hospital. Researchers tested lactate levels in 77 adults when emergency teams arrived. The goal is to find a quick, simple way to guide resuscitation decisions, but this is an early pilot study, so more research is needed.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- venous lactate measurement
- What this could lead to
- If successful, this could help doctors better predict who might recover a heartbeat during CPR, potentially guiding resuscitation efforts.
- What could go wrong
- This is a small pilot study with only 77 participants, so results may not apply broadly. Lactate levels are just one factor and may not reliably predict outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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77 people
The number who actually took part.
- Started
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Dec 2017
- Finished
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Aug 2020
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male \>18 years of age * Women over 50 years of age (ie, with amenorrhea\> 1 year). * Victim of non-traumatic cardiopulmonary arrest. * Medical decision to start or continue cardiopulmonary resuscitation. * Consent of family or person of trust if present (and patient as soon as possible). * patient affiliated to the social security Exclusion Criteria: * Refusal of family or trusted person to participate in the study * Pre-paramedical management with use of adrenaline and protection of the airways * Use of the intraosseous line from the outset or after failure of the peripheral venous pathway by the medical team outside hospital * Minor Patient * vulnerable patient under legal protection (guardianship or curators)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHU de Nice
Nice, Provences Alpes Cote d'Azur, 06000, France