Centre Hospitalier Universitaire De Nice

This study tests whether adding hyperbaric oxygen (HBO) therapy to standard UVB light treatment can improve skin color restoration in people with vitiligo. Five adults with non-segmental vitiligo will receive UVB twice a week for 24 weeks plus 40 HBO sessions over 8 weeks. The go…

This study tests whether empagliflozin, a diabetes medicine, can reduce protein leakage in urine for people with type 2 diabetes and very advanced chronic kidney disease (eGFR between 10 and 20). About 34 adults will receive either empagliflozin or a placebo for 6 weeks each, and…

This study follows 40 children with Crohn's disease or ulcerative colitis who developed severe psoriasis from anti-TNF drugs and switched to ustekinumab. Researchers want to see if their gut disease stays under control 3 to 6 months after the switch. The goal is to find a treatme…

This study tests whether a drug called GC7 can reduce harmful oxidative stress in 20 adults who have been resuscitated after a cardiac arrest. The drug aims to protect cells from damage caused when blood flow returns to the heart and brain. Researchers will measure blood markers …

This study tests a daily pill called upadacitinib for people with severe forms of lichen planus that affect the mouth, genitals, or scalp. The drug aims to calm the immune system and reduce pain, itching, and hair loss. About 56 adults will receive either the drug or a placebo fo…

This study tracks 50 adults with generalized myasthenia gravis (a rare autoimmune disease causing muscle weakness) who are taking Rozanolixizumab. Researchers want to see how symptoms change from the patient's perspective using a special questionnaire. The study is observational,…

This study looks at whether a 4D virtual simulator called Modjaw® can help doctors diagnose temporomandibular disorders (TMD) — problems with the jaw joint and muscles. About 20 adults who may have a displaced jaw disc will use the device, and results will be compared with MRI sc…

This small study tests whether a virtual reality program that uses personal memories, along with sights, sounds, smells, and tastes, can reduce apathy in older adults with dementia living in nursing homes. Ten participants will receive six weekly sessions. The main goal is to see…

This study looks at people with HIV who are 75 or older and taking many medications. Researchers want to understand how taking five or more drugs affects healthy aging and quality of life. They will collect information from 136 participants at Nice University Hospital to find way…

This study looks at how two types of nerve diseases—hereditary and inflammatory peripheral neuropathies—affect quality of life. Researchers will ask 60 adults to fill out questionnaires about their daily functioning and well-being. No treatments or changes to usual care are invol…

This study looks at the immune system of 120 women aged 18-40 with chronic pelvic pain that hasn't improved with hormone treatment. Researchers will measure specific immune markers in the blood to see if there is a unique pattern linked to the pain. The goal is to better understa…

This study aims to develop a faster, cheaper way to analyze mitochondrial DNA from muscle fibers to help diagnose mitochondrial diseases. Researchers will test a technique called digital PCR on samples from 4 patients with uncertain genetic findings. If successful, this method co…

This study explores whether involving seniors in designing their own physical activity programs leads to better long-term exercise habits. Researchers will enroll 60 adults aged 60 and older who are not yet regularly active. Participants will co-create their exercise plans and be…

This study will see if robotic surgery can be used for emergency abdominal operations. It will include 30 people who need urgent surgery for conditions like gallbladder infection or bowel blockage. The goal is to see if this approach is possible and if it leads to fewer complicat…

This study uses an online questionnaire to understand how working night shifts changes eating habits in intensive care and emergency healthcare workers. Researchers will compare their diets to those of night workers in other jobs. The goal is to find patterns that could lead to b…