GINGIVITIS
Clinical trials for GINGIVITIS explained in plain language.
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Braces and bleeding gums? new study tests which cleaning method wins
Disease control CompletedThis study looked at 30 people with braces who had gum inflammation (gingivitis). Each person received two different cleanings—one side of the mouth got a newer method called Guided Biofilm Therapy, and the other side got the traditional cleaning. Researchers checked plaque level…
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: King Abdullah University Hospital • Aim: Disease control
Last updated May 26, 2026 05:06 UTC
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Mouthwash showdown: which rinse best tames gum trouble?
Disease control CompletedThis study tested two mouthwashes in 72 adults with gum disease to see which better controls inflammation and prevents the condition from coming back. Participants used either a standard chlorhexidine rinse or a combination rinse with lower chlorhexidine plus cetylpyridinium chlo…
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: University of Siena • Aim: Disease control
Last updated May 26, 2026 05:06 UTC
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Ancient herbal mouthwash takes on modern dental standard
Disease control CompletedThis study tested whether a mouthwash made from Triphala, an Ayurvedic herbal blend, works as well as the standard chlorhexidine mouthwash for reducing plaque and gum inflammation (gingivitis). 220 adults with mild to moderate gingivitis used one of the two mouthwashes. The goal …
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: Bangladesh Medical University • Aim: Disease control
Last updated May 26, 2026 05:00 UTC
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New toothpaste and mouthwash combo takes on gingivitis
Disease control CompletedThis study tested whether a special dental routine (PerioGard toothpaste, mouthwash, and toothbrush) works better than standard products at reducing gum inflammation and plaque. 80 adults with mild to moderate gingivitis used one of the two routines for three months. The goal was…
Matched conditions: GINGIVITIS
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated May 26, 2026 05:00 UTC
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Floss vs. mouthwash: which wins the battle against plaque and gum disease?
Disease control CompletedThis study tested how well floss and three different mouthwashes (essential oil with alcohol, essential oil without alcohol, and CPC+Zn without alcohol) reduce dental plaque and gum inflammation. 228 adults with mild to moderate gum disease took part. The goal was to see which me…
Matched conditions: GINGIVITIS
Phase: PHASE4 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated May 26, 2026 04:59 UTC
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Mouthwash shows promise for healthier gums in new study
Disease control CompletedThis study tested whether a mouthwash containing cetylpyridinium chloride (CPC) could improve gum health and reduce plaque when used alongside regular brushing. 136 adults with mild to moderate gingivitis used either the CPC mouthwash or brushed alone for 12 weeks. The main goal …
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: HALEON • Aim: Disease control
Last updated May 26, 2026 04:58 UTC
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New toothbrush aims to zap gum disease in one go
Disease control CompletedThis study tested whether a full-mouth electronic toothbrush (FMET) works better than a regular electronic toothbrush for reducing gum inflammation and plaque. 94 adults with mild to moderate gingivitis took part. The FMET was used with either standard toothpaste or a foam system…
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: University of Minnesota • Aim: Disease control
Last updated May 26, 2026 04:57 UTC
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Battery toothbrush takes on plaque and gingivitis in 12-Week trial
Disease control CompletedThis study tested whether a battery-powered toothbrush, used with toothpaste, can reduce plaque and gum inflammation (gingivitis) in adults. 130 healthy adults with mild to moderate gum disease and plaque used the toothbrush for 12 weeks. Dentists measured plaque and gum health a…
Matched conditions: GINGIVITIS
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated May 26, 2026 04:37 UTC
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Toothpaste plus mouthwash beats regular brushing in gum health showdown
Disease control CompletedThis study tested whether using a special toothpaste with mouthwash and a manual toothbrush works better than regular fluoride toothpaste for reducing plaque and gum problems. 90 adults aged 18-70 with mild gum disease and plaque took part over 12 weeks. Researchers measured plaq…
Matched conditions: GINGIVITIS
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated May 26, 2026 04:37 UTC
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New toothpaste fights gum bleeding in clinical trial
Disease control CompletedThis study tested an experimental toothpaste with stannous fluoride against regular fluoride toothpaste in 154 adults with mild gum disease (gingivitis). The goal was to see if it could reduce gum bleeding and plaque buildup over 12 weeks. Results showed the special toothpaste im…
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: HALEON • Aim: Disease control
Last updated May 26, 2026 04:36 UTC
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Switching to E-Cigs may boost gum health in smokers
Disease control CompletedThis study looked at whether smokers who switch to e-cigarettes or heat-not-burn products see improvements in their gum health and tooth appearance. About 460 healthy adult smokers were followed for 18 months and compared to those who kept smoking and those who never smoked. The …
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: Eclat Srl. • Aim: Disease control
Last updated May 26, 2026 04:36 UTC
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New mouthwash takes on gold standard for gum disease
Disease control CompletedThis study tested whether a new mouthwash (MicroRepair ABX) works as well as the standard chlorhexidine mouthwash for treating gingivitis, a reversible gum inflammation caused by plaque. Forty adults with gingivitis received professional teeth cleaning and then used one of the tw…
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: University of Pavia • Aim: Disease control
Last updated May 26, 2026 04:35 UTC
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Zinc toothpaste takes on gum disease in Head-to-Head trial
Disease control CompletedThis study tested whether a new Colgate toothpaste with two types of zinc can better control plaque and gingivitis (gum inflammation) compared to a standard cavity-protection toothpaste. 86 adults with mild to moderate gum issues used one of the two toothpastes for three months. …
Matched conditions: GINGIVITIS
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated May 22, 2026 14:04 UTC
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New toothpaste and brush combo takes on plaque and gum disease
Disease control CompletedThis study compared a stannous fluoride toothpaste paired with a newly designed toothbrush to a standard toothpaste and brush for reducing plaque and gingivitis. 95 adults in Thailand used their assigned products for three months. Researchers measured plaque and gum health at the…
Matched conditions: GINGIVITIS
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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New mouthwash fights plaque and gum trouble on implants
Disease control CompletedThis study tested whether a new mouthwash with CPC, hyaluronic acid, and zinc lactate can reduce plaque and prevent gum problems around dental implants better than a standard fluoride mouthwash. 80 adults with at least two dental implants used the mouthwash for 6 months. The goal…
Matched conditions: GINGIVITIS
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated May 22, 2026 13:53 UTC
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Can black seed toothpaste tame gum inflammation?
Disease control CompletedThis study looked at whether a toothpaste made from black seed (Nigella sativa) can reduce signs of gum inflammation in 100 Indonesian soldiers with gingivitis. Researchers measured certain inflammatory markers in saliva before and after using the toothpaste. The goal was to see …
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: Universitas Airlangga • Aim: Disease control
Last updated May 22, 2026 13:51 UTC
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Toothbrush showdown: which brush beats plaque?
Disease control CompletedThis study tested how well manual toothbrushes reduce plaque and gingivitis (gum inflammation). 84 adults brushed at home with one of two toothbrushes for 6 weeks. Dentists checked their teeth and gums at the start and after 1, 3, and 6 weeks to see how much plaque and gum swelli…
Matched conditions: GINGIVITIS
Phase: PHASE2 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated May 20, 2026 12:08 UTC
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Chewing gum that may help your gums and heart
Disease control CompletedThis study tested whether a chewing gum containing dietary nitrate (a natural compound found in leafy greens and beets) could improve gum health and heart health in adults with mild to moderate gum irritation or bleeding. Thirty participants were randomly assigned to use either t…
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: University of Maryland, Baltimore • Aim: Disease control
Last updated May 20, 2026 11:55 UTC
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Special toothpaste and mouthwash take on plaque and gingivitis in new study
Disease control CompletedThis study tested whether using a stannous fluoride toothpaste together with a cetylpyridinium chloride mouthwash works better than regular fluoride toothpaste alone for reducing dental plaque and gum inflammation (gingivitis). 82 adults with mild to moderate gum disease used the…
Matched conditions: GINGIVITIS
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated May 18, 2026 12:02 UTC
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Beer ingredient toothpaste fights gum disease in new study
Disease control CompletedThis study tested two new toothpastes containing hops extract to see if they reduce gingivitis (gum inflammation) better than a standard fluoride toothpaste. 120 adults used the toothpaste for 12 weeks, and researchers measured bleeding gums and inflammation. The goal was to find…
Matched conditions: GINGIVITIS
Phase: PHASE2 • Sponsor: Procter and Gamble • Aim: Disease control
Last updated May 18, 2026 12:01 UTC
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Baking soda toothpaste takes on gum disease in new study
Disease control CompletedThis study looked at whether a toothpaste with sodium bicarbonate (baking soda) can change the bacteria in your mouth better than regular fluoride toothpaste. 74 adults with mild gum disease (gingivitis) used the toothpaste for 12 weeks. Researchers checked plaque samples to see …
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: HALEON • Aim: Disease control
Last updated May 14, 2026 12:05 UTC
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Mouthwash and toothpaste duo fights gum bleeding in new study
Disease control CompletedThis study looked at whether using a stannous fluoride toothpaste together with a cetylpyridinium chloride mouthwash can improve gum health and reduce plaque better than using regular fluoride toothpaste alone. 199 adults with gum inflammation (gingivitis) took part. The main goa…
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: HALEON • Aim: Disease control
Last updated May 11, 2026 20:54 UTC
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Herbal mouthwash challenges standard gum treatment in new study
Disease control CompletedThis study tested whether a new herbal mouthwash and gel could reduce plaque and gum inflammation as effectively as the standard chlorhexidine treatment, which can cause side effects like tooth staining and taste changes. Researchers compared the two products in 34 healthy adults…
Matched conditions: GINGIVITIS
Phase: PHASE4 • Sponsor: Stony Brook University • Aim: Disease control
Last updated Apr 21, 2026 12:44 UTC
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Spit test could spot gum disease early
Diagnosis CompletedThis study looked at whether certain proteins in saliva can help tell if someone has healthy gums, gingivitis, or periodontitis. Researchers measured three proteins (IL-6, IL-8, and LIGHT) in saliva from 60 non-smoking adults. The goal was to see if these proteins could be used a…
Matched conditions: GINGIVITIS
Sponsor: Izmir Katip Celebi University • Aim: Diagnosis
Last updated May 26, 2026 04:58 UTC
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Laser zaps braces pain and speeds up teeth shifting
Symptom relief CompletedThis study tested whether low-level laser therapy (LLLT) can reduce pain, speed up tooth movement, and improve gum health during the early phase of braces treatment. 108 adults aged 18-30 received either LLLT on their front teeth or no laser at each visit over 6 months. Researche…
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: Aga Khan University • Aim: Symptom relief
Last updated May 26, 2026 05:05 UTC
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New toothpaste fights gum bleeding in 4 weeks
Symptom relief CompletedThis study tested an experimental toothpaste with stannous fluoride, zinc, and alumina against regular fluoride toothpaste in 175 adults with mild to moderate gingivitis. Over 4 weeks, researchers measured gum bleeding and plaque buildup to see if the new toothpaste improved gum …
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: HALEON • Aim: Symptom relief
Last updated May 26, 2026 05:00 UTC
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Which retainer makes teeth whitening more comfortable? study reveals
Symptom relief CompletedThis study looked at how satisfied people were with at-home teeth whitening using two different types of retainers (Essix or Vivera) with a standard bleaching gel. Forty adults with healthy teeth and gums took part. The researchers measured satisfaction, how white teeth got, and …
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: Universidad Rey Juan Carlos • Aim: Symptom relief
Last updated May 26, 2026 04:58 UTC
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Probiotic shows promise for Braces-Related gum troubles
Symptom relief CompletedThis study looked at whether taking a specific probiotic (Limosilactobacillus reuteri) could reduce gum inflammation in adults undergoing orthodontic treatment with braces. One hundred participants with gingivitis were randomly assigned to receive the probiotic or no supplement. …
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: Medical University of Warsaw • Aim: Symptom relief
Last updated May 26, 2026 04:34 UTC
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Power brush and rinse combo takes on gingivitis in Six-Week trial
Symptom relief CompletedThis study tested whether using a power toothbrush and mouth rinse twice daily for six weeks reduces gum bleeding and inflammation better than a manual toothbrush alone. Sixty-nine adults with gingivitis were randomly assigned to either the power brush plus rinse group or the man…
Matched conditions: GINGIVITIS
Phase: PHASE4 • Sponsor: Procter and Gamble • Aim: Symptom relief
Last updated May 20, 2026 11:56 UTC
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Gum disease and kidney trouble: new clues from saliva and blood
Knowledge-focused CompletedThis study looked at 126 people with type 2 diabetes, some with kidney disease (diabetic nephropathy) and some without. Researchers measured three inflammatory markers (NGAL, TNF-α, and IL-10) in both saliva and blood to see how they relate to gum health. The goal was to better u…
Matched conditions: GINGIVITIS
Sponsor: Pamukkale University • Aim: Knowledge-focused
Last updated May 26, 2026 04:58 UTC
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Jaw bone secrets revealed: gum Therapy's hidden impact
Knowledge-focused CompletedThis study looked at 69 people with gum disease (periodontitis or gingivitis) to see if non-surgical treatment changes the bone supporting their teeth. Researchers used special X-ray analysis to compare bone structure before and 6 months after treatment. The goal was to better un…
Matched conditions: GINGIVITIS
Sponsor: Akdeniz University • Aim: Knowledge-focused
Last updated May 26, 2026 04:58 UTC
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Gum disease disrupts body's internal clock, study finds
Knowledge-focused CompletedThis study looked at whether gum disease (gingivitis or periodontitis) changes how the body's natural clock works in gum tissue. Researchers studied 60 healthy adults with similar sleep patterns. They collected small gum tissue samples and measured clock-related genes and protein…
Matched conditions: GINGIVITIS
Sponsor: Inonu University • Aim: Knowledge-focused
Last updated May 07, 2026 18:42 UTC
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Gum disease study tracks mouth's inflammation signals before and after cleaning
Knowledge-focused CompletedThis study looked at two substances in the fluid around teeth—fractalkine and CX3CR1—that are linked to inflammation. Researchers measured them in 90 adults with healthy gums, gingivitis, or periodontitis before and after a deep cleaning. The goal was to see how these markers cha…
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: Giresun University • Aim: Knowledge-focused
Last updated May 07, 2026 18:41 UTC