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Ancient herbal mouthwash takes on modern standard for gum disease

NCT ID NCT07426393

Disease control Sponsor: Bangladesh Medical University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a mouthwash made from Triphala, an Ayurvedic herbal formula, works as well as the standard chlorhexidine mouthwash for reducing plaque and gum inflammation. 220 adults with mild to moderate gingivitis used one of the two mouthwashes twice daily for 30 days. Researchers measured plaque, gum health, and bleeding to see if Triphala could be a natural alternative with fewer side effects.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Triphala mouthwash (6%) and chlorhexidine mouthwash (0.2%)
What this could lead to
If Triphala works as well as chlorhexidine, it could offer a natural, pleasant-tasting alternative for managing gum disease.
What could go wrong
This is a small, completed trial with no phase designation, so results may not be widely applicable. Triphala may not be as effective as standard treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

220 people

The number who actually took part.

Started

Mar 2025

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age groups of 18-45 years with * Mild to moderate gingivitis, * Patients with a minimum of 20 teeth, and * Patients who have not undergone periodontal treatment in the past 6 months. Exclusion Criteria: * Use of anti-inflammatory drugs and antibiotics in previous 6 months; * Individuals with prosthetic appliances or orthodontic appliances that would interfere with evaluation * Allergy to Triphala and Chlorhexidine used in the study; * Smokers or users of tobacco in any form * Lactating females or pregnant women * Mental-retarded patients.

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Conditions

The condition(s) this trial relates to.

gingivitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Gingivitis

Contacts and locations

Locations

  • Bangladesh Medical University

    Dhaka, Bangladesh

More trials for these conditions

Other studies related to the condition(s) this trial covers.