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Gum disease clue found in spit and gum juice?

NCT ID NCT07497828

Knowledge-focused Sponsor: Ordu University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study measured levels of a protein called IL-36α in saliva and gum fluid from 80 people with gum disease, gingivitis, or healthy gums. The goal was to see if this protein is linked to gum inflammation and damage. No treatment was given; it was purely an observational study to gather knowledge.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help researchers understand how IL-36α is involved in gum disease, potentially pointing toward new ways to diagnose or treat it.
What could go wrong
This is an observational study that only measures a substance in body fluids. It does not test any treatment, so it cannot directly lead to a cure or therapy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

80 people

The number who actually took part.

Started

Dec 2023

Finished

Jan 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 55 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * at least 20 teeth * older than 18 years Exclusion Criteria: * any systemic disease * pregnant or lactating * history of radiotherapy or chemotherapy * used antibiotics or any anti-inflammatory medication * smokers * had undergone periodontal treatment within the previous 6 months

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Conditions

The condition(s) this trial relates to.

gingivitis periodontal disorder periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cytokine Gingival crevicular fluid Periodontal diseases SALIVA

Contacts and locations

Locations

  • Ordu University

    Ordu, 52100, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.