GINGIVITIS

This study compares a stannous fluoride toothpaste to regular Colgate Cavity Protection toothpaste. About 100 adults aged 18-70 will brush with one of the two toothpastes to see which better reduces bacteria on teeth, tongue, cheeks, gums, and saliva. The goal is to control plaqu…

This study compares two types of noninvasive dental care for 160 pregnant people with gum disease. Participants get free dental check-ups, cleanings, and supplies. The goal is to see which approach better reduces gum inflammation and improves oral health habits and birth outcomes…

This study tests whether a toothpaste containing chitosan can reduce plaque, gingivitis, and gum bleeding better than a standard toothpaste. About 90 adults aged 18–70 with good general health will brush twice daily for a set period. Researchers will measure gum inflammation, pla…

This study compares a homemade herbal mouthwash to chlorhexidine, the standard treatment, for controlling plaque buildup in people with gingivitis (early gum disease). The goal is to find a safer alternative with fewer side effects. Twelve adults with plaque-induced gingivitis wi…

This study aims to develop a mouth rinse from stingless bee honey as a gentler alternative to the standard chemical rinse, chlorhexidine, which can cause tooth staining and mouth irritation. The research involves lab tests and a small pilot study with 60 adults who have mild gum …

This study tests whether a probiotic lozenge containing a special strain of Streptococcus salivarius (SALI-10) can reduce gum inflammation and bad breath. Sixty adults with gingivitis will take the lozenge or a placebo twice daily for four weeks. The goal is to see if the probiot…

This study will see if a 3D dental scanner can accurately measure plaque on teeth, compared to the traditional method of using a dye and visual check. Twenty adults with at least 20 natural teeth and visible plaque will be scanned before and after brushing. The goal is to develop…

This study will check if simple methods like mouth photos, smartphone images, X-rays, and questionnaires can accurately find gum disease compared to a standard dental exam. About 2,000 adults will take part across five centers. The goal is to develop AI tools that make screening …

This study aims to see if a self-reported questionnaire can accurately identify gum disease (periodontitis or gingivitis) in adults in Saudi Arabia. About 291 participants will fill out the questionnaire and then receive a standard dental exam on the same visit. The results will …

This study will test whether chewing xylitol-containing gum during pregnancy can reduce the risk of preterm birth and low birthweight. About 6,000 pregnant women in Malawi will be randomly assigned to chew gum with a high or low dose of xylitol, or a placebo gum. The goal is to s…

This study tests whether a special mouthwash can improve gum health in adults with mild-to-moderate gingivitis. Thirty participants will use the mouthwash daily for four weeks and visit the dentist for check-ups. The main goal is to see if gum inflammation and bleeding get better…

This study tests whether a personalized oral hygiene training method (iTOP) is better than standard instruction for improving gum health in 60 adults with braces and gingivitis. Participants will receive one-on-one training or standard video/model demonstrations, and their plaque…

This study explores whether a health app and follow-up video chats with a dental hygienist can motivate teenagers (ages 16-17) to improve their oral hygiene and reduce gingivitis. About 25 teens with gum inflammation will test the approach. The goal is to see if this digital meth…

This study looks at how having a disrupted sleep schedule, like working night shifts, might affect gum health. Researchers will measure specific clock proteins and immune markers in the gum fluid of 116 people, comparing those with normal sleep to those with disrupted sleep, and …

This study looks at how three different ways of cleaning clear aligners affect the bacteria in the mouth and gum health. Twenty-one adults will try each method for one month: brushing with toothpaste, using a special mouthwash, or using an oxygen-based cleaner. The goal is to see…