Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Night shift Workers' gums under the microscope: body clock linked to inflammation

NCT ID NCT07592052

Knowledge-focused Sponsor: Inonu University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how a disrupted body clock (like in night-shift workers) affects gum inflammation. Researchers will measure clock proteins and immune markers in the gum fluid of 116 people with and without gum disease. The goal is to understand the link between sleep-wake cycles and oral health.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 116 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Systemically healthy volunteers aged 20-50 years presenting to Inonu University Faculty of Dentistry, Department of Periodontology. The study population includes individuals with normal circadian rhythm and night-shift workers with circadian rhythm disruption. Participants are classified as periodontally healthy or with gingivitis based on clinical periodontal examination. Circadian rhythm status is verified using the Morningness-Eveningness Questionnaire (MEQ) and Munich Chronotype Questionnaire (MCTQ).

Ages

20 to 50 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged between 20 and 50 years * Systemically healthy * Diagnosed as periodontally healthy or with gingivitis based on clinical periodontal examination * Having at least 20 natural teeth in the oral cavity * Willing to provide written informed consent * Agreeing to participate in circadian rhythm assessment and completing the Morningness-Eveningness Questionnaire (MEQ) and Munich Chronotype Questionnaire (MCTQ) * Sleep duration of 6-9 hours per day * For periodontally healthy: PD \<=3 mm, BOP \<10%, CAL=0, no radiographic bone loss * For gingivitis: PD \<=3 mm, 10%\<=BOP\<=30%, CAL=0, no radiographic bone loss * For circadian rhythm disruption group: being a night-shift worker Exclusion Criteria: * Use of antioxidant or melatonin supplements * Presence of any systemic disease * Use of antibiotics, anti-inflammatory drugs, or immunosuppressants within the past 3 months * Having received periodontal treatment within the past 6 months * Pregnancy or lactation * Use of tobacco or tobacco products * Presence of acute oral infection, abscess, or advanced periodontal disease * Currently undergoing orthodontic treatment or having fixed orthodontic appliances * Inability to comply with study procedures or refusal to provide informed consent * Self-reported sleep duration less than 6 hours or greater than 9 hours per day

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Circadian rhythm disruption are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

circadian rhythm sleep disorder circadian rhythm sleep disorder, shift work type gingivitis periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Circadian rhythm disruption Circadian rhythm sleep disorder, shift work type Gingivitis Periodontal inflammation

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Inönü University Faculty of Dentistry, Department of Periodontology

    Malatya, Malatya, 44210, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.