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Mouthwash showdown: new formula takes on classic antiseptic for healthier gums

NCT ID NCT07088653

Symptom relief Sponsor: University of Pavia Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two mouthwashes—a standard antiseptic (chlorhexidine) and a new one (MicroRepair ABX)—in 40 adults with gingivitis (gum inflammation). After a professional cleaning, participants used their assigned mouthwash twice daily for 14 days. Researchers measured gum bleeding, plaque buildup, and a saliva marker of inflammation over 6 months to see if the new mouthwash works as well as the standard one.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Aug 2025

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged between 18 and 70 years * Presence of generalized plaque-induced gingivitis, defined by bleeding on probing (BoP) ≥30% in the absence of clinical attachment loss, with probing pocket depth ≤3 mm at ≥90% of sites * At least 20 natural teeth * Good general health (ASA I or II) * Signed written informed consent * Willingness to comply with study protocol and attend all follow-up visits Exclusion Criteria: * Periodontitis, defined as interdental clinical attachment loss (CAL) at ≥2 non-adjacent teeth * Systemic conditions known to affect periodontal status, including diabetes mellitus and immunodeficiencies * Antibiotic or anti-inflammatory therapy within the previous 3 months * Professional dental prophylaxis within the previous 3 months * Pregnancy or breastfeeding * Known allergy to chlorhexidine or MicroRepair components * Use of orthodontic appliances or removable prostheses * Smoking more than 10 cigarettes per day * Participation in other clinical trials within the previous 6 months

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Conditions

The condition(s) this trial relates to.

Dental Plaque gingivitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dental plaque Gingival inflammation Gingivitis

Contacts and locations

Locations

  • Unit of Orthodontics and Pediatric Dentistry - Section of Dentistry - Department of Clinical, Surgical, Diagnostic and Pediatrics - University of Pavia

    Pavia, Lombardy, 27100, Italy

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