Could a blood test reveal how bad your gum disease is?
NCT ID NCT07628803
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study looked at 160 healthy adults to see if a blood test marker called Pan-Immune-Inflammation Value (PIV) is linked to the severity of gum disease. Researchers measured gum inflammation and compared it to PIV from routine blood work. The goal was to explore if this blood marker could help assess gum disease without a dental exam.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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160 people
The number who actually took part.
- Started
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Dec 2025
- Finished
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May 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Systemically healthy adults aged 18 years and older who present to the Department of Periodontology, Faculty of Dentistry, Bolu Abant Izzet Baysal University, and who are diagnosed as periodontally healthy, having gingivitis, or having Stage III-IV periodontitis according to the 2017 World Workshop Classification of Periodontal and Peri-Implant Diseases and Conditions.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18 years and older * Systemically healthy individuals * Complete blood count performed within the previous 3 months * Diagnosis of periodontal health, gingivitis, or Stage III-IV periodontitis according to the 2017 World Workshop Classification of Periodontal and Peri-Implant Diseases and Conditions * Willingness to provide written informed consent Exclusion Criteria: * Pregnancy or lactation- History of systemic diseases that may affect periodontal tissues * Use of antibiotics or anti-inflammatory drugs within the previous 3 months * Periodontal treatment within the previous 6 months * Presence of infectious diseases such as HIV, hepatitis B, or tuberculosis
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Faculty of Dentistry, Bolu Abant İzzet Baysal University, Department of Periodontics
Bolu, Central, 14100, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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