Can a better brushing routine beat gingivitis?
NCT ID NCT07211061
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a specific routine—using a power toothbrush and mouth rinse twice daily—reduces gum bleeding and inflammation better than a manual toothbrush alone. 69 adults with gingivitis participated for 6 weeks. Researchers measured gum health at the start and after 1, 3, and 6 weeks.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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69 people
The number who actually took part.
- Started
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Sep 2011
- Finished
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Nov 2011
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Provide written informed consent to participate in the study; * Be 18 years of age or older; * Agree not to participate in any other oral/dental product studies during the course of this study; * Agree to delay any elective dentistry (including dental prophylaxis) until the study has been completed; * Agree to refrain from any form of non-specified oral hygiene during the treatment periods, including but not limited to the use of products such as floss or whitening products; * Have a Baseline MGI score of at least 1.75 but not greater than 2.3; * Have at least 20 bleeding sites (sites with a score of 1 or 2 on the GBI index); * Agree to return for all scheduled visits and follow study procedures; * Be in good general health, as determined by the Investigator/designee based on a review of the health history/update for participation in the study. Exclusion Criteria: * Have had a dental prophylaxis within 2 weeks of Baseline visit; * Have taken antibiotics or used anti-gingivitis / anti-bacterial oral care products such as chlorhexidine or Listerine within 2 weeks of plaque sampling visits; * Have rampant caries, open or untreated caries, severe gingivitis, or advanced periodontitis requiring prompt treatment; or, * Need an antibiotic prophylaxis prior to dental visits, * Present with any disease or condition(s) that could be expected to interfere with examination procedures or the subject's safe completion of the study, * Are pregnant (Self-reported) or lactating.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Bio-Sci Research (Out of Business)
Las Vegas, Nevada, 89121, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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