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Battery toothbrush beats manual in gum health showdown

NCT ID NCT07224828

Disease control Sponsor: Colgate Palmolive Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jul 31, 2026 · Updated 2 times

Summary

This completed Phase 3 study tested whether a battery toothbrush paired with a stannous fluoride toothpaste is more effective at reducing plaque and gingivitis than a regular fluoride toothpaste with a manual toothbrush. 130 adults with mild gum disease brushed twice daily for 12 weeks. Dentists measured gum inflammation and plaque levels at the start and end. The goal was to see if the battery-powered option leads to better oral health.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Stannous fluoride toothpaste with battery toothbrush
What this could lead to
If it works, this could show that a battery toothbrush with special toothpaste is a better option for everyday oral care to reduce plaque and gum inflammation.
What could go wrong
This is a completed Phase 3 trial, but it only included 130 generally healthy adults with mild gum disease, so results may not apply to everyone. Also, the improvement may be small and not clinically meaningful.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

130 people

The number who actually took part.

Started

Oct 2025

Finished

Jan 2026

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male and Female, age 18-70, inclusive. * Availability for the 12-week duration of the clinical research study. * Good general health at the discretion of the dental examiner or study investigators. * Minimum of 20 permanent natural teeth (excluding third molars). * Initial gingivitis index of at least 1.0 as determined by the use of the Loe and Silness Gingival Index. * Initial mean plaque index of at least 0.6 as determined by Rustogi Modification of the Navy plaque index. * Signed Informed Consent Form Exclusion Criteria: * Presence of orthodontic appliances. * Presence of partial removable dentures. * Oral pathology, chronic disease or tumor(s) of the soft or hard tissues of the oral cavity. * Advanced periodontal disease (purulent exudate, tooth mobility, and/or extensive loss of periodontal attachment or alveolar bone). * Five or more carious lesions requiring immediate restorative treatment. * Use of anticonvulsants, sedatives, tranquilizers, anti-inflammatory or daily analgesics within one month prior to the start of the study or scheduled to start such intake during the course of the study. * Use of antibiotics any time during the one-month period prior to entry into the study. * Ongoing use of medications known to affect gingival tissues (i.e. calcium channel blockers, phenytoin, cyclosporine) and/or on any prescription medicines that might interfere with the study outcome. * Participation in any other clinical study. * Self-reported pregnancy and/or breastfeeding. * Dental prophylaxis within the past three weeks prior to baseline examinations. * Current allergies and/or history of allergic reactions to oral care products, personal care consumer products, or any of their ingredients.

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Conditions

The condition(s) this trial relates to.

gingivitis Plaque, Amyloid

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Gingivitis Plaque

Contacts and locations

Locations

  • Dental Research Associates, Inc.

    San Juan, 00927, Puerto Rico

More trials for these conditions

Other studies related to the condition(s) this trial covers.