University Of Washington

This study is testing a new system designed to help more people with mental health conditions get better care in Mozambique. It focuses on training and supporting local health workers to help patients stay in treatment, take their medication, and improve their daily functioning. …

This study is testing a combination of three immunotherapy drugs for patients with advanced Merkel cell carcinoma, a rare and aggressive skin cancer, that has spread and stopped responding to a common first-line treatment. The drugs are designed to work together to reactivate the…

This study is testing whether the immunotherapy drug nivolumab can help control blood cancers that have returned, stopped responding, or are still detectable after a patient has already received CAR-T cell therapy. It is for adults with specific types of lymphoma, leukemia, or mu…

This study is testing a support program for people leaving the hospital who are being treated for opioid addiction and also use methamphetamine. The program combines a patient navigator (a coach), a smartphone app for medication check-ins, and small rewards to help people connect…

This study tests two different approaches to help people who have inherited cancer risk genes get the recommended screenings and preventive surgeries after genetic testing. Researchers will compare a simple web-based resource program and a more personal outreach program with a ca…

This early-stage study is testing the safety and immune response of a new vaccine called STEMVAC in patients with advanced HER2-negative breast cancer. The vaccine aims to train the body's immune system to recognize and attack cancer cells, particularly those that are resistant t…

This study is testing whether the drug abemaciclib can help control advanced digestive system neuroendocrine tumors that have spread and stopped responding to standard treatments. The drug works by blocking enzymes that tumor cells need to grow. About 20 patients with these speci…

This study is testing whether simple urine tests that check if people are taking their HIV medication properly and measure their virus levels can help people stay on treatment longer and keep the virus under control. The research involves 539 people in South Africa who are starti…

This study is testing whether a mobile phone program can help women living with HIV better plan their families and reproductive health. The program sends automated text messages and allows for two-way communication with a counselor. Researchers want to see if this support helps w…

This study is testing whether different types of social support can help Black women complete their prescribed endometrial cancer treatments and feel less alone. Researchers are comparing weekly group meetings, one-on-one peer support, and standard care to see which works best. T…

This study is testing if a two-drug combination can stop ovarian, fallopian tube, or primary peritoneal cancer from getting worse after it has come back. The treatment pairs an immunotherapy drug (pembrolizumab) that helps the immune system fight cancer with a chemotherapy drug (…

This study is testing a new, personalized method for treating multiple myeloma that has returned or stopped responding to standard drugs. Doctors take a sample of a patient's cancer cells and test many different drugs on them in the lab to see which ones work best. The goal is to…

This study aims to find the best way to help women recover from PTSD and problematic alcohol use after experiencing sexual assault. Researchers are testing different telehealth counseling approaches to see whether it's better to address PTSD symptoms first, alcohol use first, or …

This study is testing a combination of four medications for people with multiple myeloma that has come back or stopped responding to prior treatments. The goal is to see if this drug combination can effectively control the cancer and extend the time patients live without their di…

This study is testing whether adding an anti-inflammatory drug (golimumab) to a standard prostate cancer hormone blocker (apalutamide) can better control a very advanced form of the disease. It's for men whose cancer has spread and stopped responding to standard hormone treatment…

This study is testing whether a medication called emicizumab can safely prevent bleeding episodes in adults with acquired hemophilia A, a rare but serious condition where the immune system attacks blood clotting factors. About 51 participants will receive weekly injections of the…

This small, early-stage study is testing whether therapy sessions combined with the drug MDMA can help people diagnosed with pathological narcissism. Twelve participants will receive three MDMA-assisted therapy sessions over several months, followed by a six-month observation per…

This study aimed to test a new therapy model called 'Connections' for young people (ages 13-30) experiencing suicidal thoughts. The goal was to see if combining established therapy principles with standard primary care could improve the patient-provider relationship and potential…

This study is testing whether a new support program started in the emergency room can help people with opioid addiction. The program provides education, motivation, help starting medication treatment, and three months of follow-up care. Researchers want to see if this approach he…

This study is testing an experimental vaccine called STEMVAC in people with early-stage triple-negative breast cancer who have already finished their standard treatments. The goal is to see if the vaccine can safely 'wake up' the immune system to recognize and attack specific pro…

This study is testing whether a drug called avelumab can help prevent Merkel cell carcinoma from returning in patients whose cancer had spread to lymph nodes. After completing standard surgery and/or radiation, 101 participants will receive either avelumab or a placebo via IV for…

This study is testing a two-drug combination for people with certain slow-growing types of B-cell lymphoma who have not yet received treatment. The goal is to see how well the pill ixazomib works when given with the antibody drug rituximab to shrink tumors and control the cancer.…

This early-stage trial is testing a combination of two drugs, niraparib and dostarlimab, for people with advanced breast, ovarian, pancreatic, or related cancers that have a specific genetic change (BRCA mutation) and have stopped responding to standard treatments. The goal is to…

This study is testing whether adding a pill called acalabrutinib makes a powerful cell therapy (CAR-T) work better and safer for people with certain aggressive B-cell lymphomas. The trial enrolled 23 adults to see if the combination is safe and can help control the cancer. Resear…

This study compares two approaches for people whose diverticulitis significantly affects their quality of life. Researchers are testing whether elective colon surgery works better than optimized medication management at improving patients' symptoms and daily life. The trial invol…

This study tests whether using home blood pressure readings is better than using clinic readings before dialysis to guide treatment for 200 people with kidney failure. The goal is to reduce episodes of dangerously low blood pressure during dialysis treatments. Researchers will ad…

This study is testing a new type of MRI scan to help find breast cancer in women with dense breast tissue. Dense breasts can make cancers harder to see on a standard mammogram. The new scan is quick, doesn't use a contrast dye, and aims to be more accurate than ultrasound and saf…

This study is testing a new type of PET scan called 68Ga-PSMA-11 to see if it can better find and track prostate cancer. It enrolled 141 men with different stages of prostate cancer to see if this scan changes how doctors plan their treatment. The goal is to improve how doctors m…

This study is testing whether new computer software can make ultrasound images better at finding and measuring kidney stones. Researchers will scan 370 adult patients who have kidney stones visible on X-rays. They will compare the new ultrasound images to standard X-rays, CT scan…

This large study aims to help more pregnant and postpartum women in Kenya start and stay on medication to prevent HIV. It tests a support program for health clinics, including training and quality improvement, to make offering this prevention a regular part of maternal care. The …

This study tests whether a simple writing exercise can help college graduates reduce risky drinking as they transition to adult life. Researchers are enrolling 468 soon-to-graduate students who drink at concerning levels and have some interest in changing their habits. Participan…

This study is testing if a simple 20-minute writing exercise can help recent high school graduates make healthier decisions about alcohol. Researchers want to see if writing about a person's desired or feared future self can change how they see themselves in relation to drinking …

This study is testing a nurse care management program designed to help adults in rural areas who live with chronic pain. The program provides care coordination, teaches coping skills through therapy, and helps connect patients to a home-based exercise program. The goal is to see …

This study aims to see if sending caring text messages to stressed or distressed veterans and service members helps reduce their emotional distress and thoughts of suicide. Researchers are comparing two groups: one receives these supportive texts along with the best available res…

This study is testing whether adding a special digital app and web platform can improve depression care for people undergoing cancer treatment. It compares this tech-enhanced approach to the usual collaborative care methods. The goal is to see if the technology helps patients and…

This study is testing whether doing computerized brain training exercises in the morning or late afternoon works better for older adults recovering from a stay in the intensive care unit (ICU). Researchers want to see if the timing of these exercises can help improve thinking ski…

This study is testing a program designed to help cancer survivors feel less lonely and more connected. Researchers are adapting a 'social prescribing' approach that helps people find social activities and build supportive networks. The pilot study involves 36 cancer survivors who…

This study is testing a text-message chatbot named Cecebot, designed to help breast cancer survivors who have trouble sleeping. The chatbot provides sleep coaching and gentle activity suggestions based on proven therapies. Researchers want to see if using the chatbot for 6 weeks …

This study aims to help patients and doctors make better decisions when bladder cancer returns after initial treatment. Researchers are following 570 patients who choose either bladder removal surgery or additional drug therapy to see which approach leads to better quality of lif…

This study is testing whether a special type of MRI scan can provide more detailed information about a very early form of breast cancer called DCIS, which is often first seen as tiny white spots (calcifications) on a mammogram. Researchers are enrolling 122 women who have these s…

This study is testing whether a special educational website can help people with advanced cystic fibrosis feel more prepared to talk with their doctors about lung transplant. Researchers want to see if the website improves knowledge and readiness for these important conversations…

This study is testing a special type of PET scan to see if it can measure how breast cancer tumors respond to hormone therapy. Researchers will scan patients before, during, and after treatment to see if changes in the scan images match how well the therapy is working. The goal i…

This study aims to see if MRI scans taken before and after treatment can help doctors understand how HER2-positive breast cancer responds to therapy. Researchers will scan 13 patients receiving standard anti-HER2 drugs before surgery to see if imaging changes match what's seen in…

This study aims to learn how to match adults with chronic pain to the talk therapy most likely to help them. Researchers are testing if brain activity and personal traits can predict who benefits most from Cognitive Behavioral Therapy (CBT), mindfulness therapy, or hypnotherapy. …